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SI 抗体 (N-Term)

适用: 人, 小鼠, 大鼠 WB, FACS, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7603154
发货至: 中国
  • 抗原 See all SI products
    SI
    抗原表位
    • 1
    • 1
    N-Term
    适用
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 3
    • 1
    克隆类型
    • 3
    • 1
    多克隆
    标记
    • 4
    This SI antibody is un-conjugated
    应用范围
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)
    原理
    Anti-SI Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-SI Antibody Picoband® (ABIN7603154). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human SI, which shares 86.1% amino acid (aa) sequence identity with rat SI.
    亚型
    IgG
  • 应用备注
    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
    Flow Cytometry(Fixed), 1-3 μg/1x106 cells
    1. Birkenmeier, E. H., Rowe, L. B., Leeper, L. L., Henning, S. J. The sucrase-isomaltase structural gene (Si-s) and a regulatory gene (Si-r) are closely linked to esterase-26 (Es-26) on mouse chromosome 3. Mammalian Genome 4: 531-536, 1993. 2. Chantret, I., Lacasa, M., Chevalier, G., Ruf, J., Islam, I., Mantei, N., Edwards, Y., Swallow, D., Rousset, M. Sequence of the complete cDNA and the 5-prime structure of the human sucrase-isomaltase gene: possible homology with a yeast glucoamylase. Biochem. J. 285: 915-923, 1992. 3. Davis, M. B., Green, F. R., West, L. F., Kearney, A., Povey, S., Swallow, D. M. Mapping of the gene encoding human sucrase-isomaltase (SI) to chromosome 3q25-26. (Abstract) Cytogenet. Cell Genet. 46: 604, 1987.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    SI
    Abstract
    SI 产品
    背景

    Synonyms: Sucrase-isomaltase, intestinal, Sucrase, Isomaltase, SI

    Tissue Specificity: Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon.

    Background: This gene is mapped to 3q26.1. It encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.

    分子量
    209 kDa
    基因ID
    6476
    UniProt
    P14410
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