FAM33A 抗体 (N-Term)
Quick Overview for FAM33A 抗体 (N-Term) (ABIN7603134)
抗原
See all FAM33A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-SKA2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SKA2 Antibody Picoband® (ABIN7603134). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human SKA2, which shares 90.0% amino acid (aa) sequence identity with both mouse and rat SKA2.
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亚型
- IgG
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anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (AA 1-121) antibody
FAM33A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (N-Term) antibodyFAM33A 适用: 人, 小鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (AA 9-37), (N-Term) antibodyFAM33A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31468 unconjugated
anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (AA 16-45), (N-Term) antibodyFAM33A 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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"Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
"1. Hanisch A, Silljé HH, Nigg EA (November 2006). "Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2". The EMBO Journal. 25 (23): 5504-15. 2. Wang Y, Zhang Y, Zhang C, Weng H, Li Y, Cai W, Xie M, Long Y, Ai Q, Liu Z, Du G, Wang S, Niu Y, Song F, Ozaki T, Bu Y (September 2015). "The gene pair PRR11 and SKA2 shares a NF-Y-regulated biional promoter and contributes to lung cancer development". Biochimica et Biophysica Acta. 1849 (9): 1133-44. 3. Guintivano J, Brown T, Newcomer A, Jones M, Cox O, Maher BS, Eaton WW, Payne JL, Wilcox HC, Kaminsky ZA (December 2014). "Identification and replication of a combined epigenetic and genetic biomarker predicting suicide and suicidal behaviors". The American Journal of Psychiatry. 171 (12): 1287-96. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))
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别名
- SKA2
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背景
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Synonyms: Spindle and kinetochore-associated protein 2, Protein FAM33A, SKA2, FAM33A
Background: Spindle and kinetochore-associated protein 2 is a protein that in humans is encoded by the SKA2 gene found in chromosome 17.SKA2 is a part of a spindle and kinetochore associated complex also including SKA1 and SKA3 which is responsible for onset of the anaphase in mitosis by regulating chromosomal segregation. SKA2 may function as a prognostic gene marker for identifying lung cancer[3] as well as a proposed biomarker for suicidal tendencies and post-traumatic stress disorders.[4][5] The SKA2 gene contains one single-nucleotide polymorphism (SNP) rs7208505 located in the 3' UTR. This genetic variant containing a cytosine (existing in the less common allele) instead of thymine along with epigenetic modification (such as DNA methylation) is correlated with suicidal tendencies and post-traumatic stress
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分子量
- 20 kDa
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基因ID
- 348235
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途径
- M Phase
抗原
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