Synaptophysin 抗体 (N-Term)
Quick Overview for Synaptophysin 抗体 (N-Term) (ABIN7603120)
抗原
See all Synaptophysin (SYP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Synaptophysin/SYP Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Synaptophysin/SYP Picoband® Antibody (ABIN7603120). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Synaptophysin/SYP, which shares 91.3% amino acid (aa) sequence identity with both mouse and rat Synaptophysin/SYP.
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亚型
- IgG
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anti-Synaptophysin (SYP) (AA 150-250) antibody
SYP 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Synaptophysin (SYP) (C-Term) antibodySYP 适用: 人 WB, IF, IHC (p), ICC, IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Synaptophysin (SYP) (AA 225-253), (C-Term) antibodySYP 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB32966 unconjugated
anti-Synaptophysin (SYP) (AA 225-253), (C-Term) antibodySYP 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32966 unconjugated
anti-Synaptophysin (SYP) (Internal Region) antibodySYP 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synaptophysin (SYP) antibodySYP 适用: 人, 犬 WB, IF 宿主: 小鼠 Monoclonal 5H2 unconjugated
anti-Synaptophysin (SYP) (N-Term) antibodySYP 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptophysin (SYP) antibodyMicroarray verified SYP 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB551901 unconjugated
anti-Synaptophysin (SYP) (AA 1-313) antibodySYP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B3 unconjugated
anti-Synaptophysin (SYP) antibodySYP 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E2 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section, 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Mouse, Rat
1. Cremin, S. M., Greer, W. L., Bodok-Nutzati, R., Schwartz, M., Peacocke, M., Siminovitch, K. A. Linkage of Wiskott-Aldrich syndrome with three marker loci, DXS426, SYP and TFE3, which map to the Xp11.3-p11.22 region. Hum. Genet. 92: 250-253, 1993. 2. Janz, R., Sudhof, T. C., Hammer, R. E., Unni, V., Siegelbaum, S. A., Bolshakov, V. Y. Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. Neuron 24: 687-700, 1999. 3. Kwon, S. E., Chapman, E. R. Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron 70: 847-854, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Synaptophysin (SYP)
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别名
- SYP
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背景
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Synonyms: Synaptophysin, Major synaptic vesicle protein p38, SYP
Tissue Specificity: Ubiquitous in adult tissues. Detected in osteoblasts of the perichondrium in the developing limb of 12-week old embryos. Isoform 1 is detected in fetal brain, lung, kidney and testis. Isoform 2 is detected in fetal testis, and at much lower levels in fetal brain, lung and kidney.
Background: Synaptophysin, also known as the major synaptic vesicle protein p38, is a protein that in humans is encoded by the SYP gene. It is mapped to Xp11.23. This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability.
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分子量
- 38 kDa
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基因ID
- 6855
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UniProt
- P08247
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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