RNH1 抗体 (N-Term)
Quick Overview for RNH1 抗体 (N-Term) (ABIN7603117)
抗原
See all RNH1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband® (monoclonal, 4F3)
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband® (monoclonal, 4F3) (ABIN7603117). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human RNH1, different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.
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亚型
- IgG2b
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. "Entrez Gene: RNH1 ribonuclease/angiogenin inhibitor 1". 2. Weremowicz S, Fox EA, Morton CC, Vallee BL (1991). "The placental ribonuclease inhibitor (RNH) gene is located on chromosome subband 11p15.5.". Genomics 8(4): 717-21. 3. Zneimer SM, Crawford D, Schneider NR, Beutler B (1991). "Mapping of the human ribonuclease inhibitor gene (RNH) to chromosome 11p15 by in situ hybridization.". Genomics 8 (1): 175-8. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))
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别名
- RNH1
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背景
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Synonyms: AW546468 antibody, C80305 antibody, MGC18200 antibody, MGC4569 antibody, MGC54054 antibody, OTTHUMP00000147628 antibody, OTTHUMP00000229864 antibody, OTTHUMP00000229865 antibody, OTTHUMP00000229866 antibody, OTTHUMP00000229870 antibody, OTTHUMP00000229871 antibody, OTTHUMP00000229872 antibody, Placental ribonuclease inhibitor antibody, Placental RNase inhibitor antibody, PRI antibody, RAI antibody, RI antibody, Ribonuclease inhibitor antibody, Ribonuclease/angiogenin inhibitor 1 antibody, Ribonuclease/angiogenin inhibitor antibody, RINI_HUMAN antibody, RNase inhibitor antibody, RNH 1 antibody, RNH antibody, RNH1 antibody, Rnh1 ribonuclease/angiogenin inhibitor 1 antibody
Background: Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular Rnases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover, the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.
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分子量
- 45 kDa
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基因ID
- 6050
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UniProt
- P13489
抗原
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