Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (N-Term) 抗体
Quick Overview for Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (N-Term) 抗体 (ABIN7603115)
抗原
See all Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-ND4/Mtnd4 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ND4/Mtnd4 Antibody (ABIN7603115). Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of rat ND4/Mtnd4, which shares 82.3% amino acid (aa) sequence identity with mouse ND4/Mtnd4.
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亚型
- IgG
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anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) antibody
MT-ND4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (AA 406-459) antibodyMT-ND4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (AA 350-450) antibodyMT-ND4 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) antibodyMT-ND4 适用: 小鼠, 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Rat
1. Arizmendi, J. M., Skehel, J. M., Runswick, M. J., Fearnley, I. M., Walker, J. E. Complementary DNA sequences of two 14.5 kDa subunits of NADH:ubiquinone oxidoreductase from bovine heart mitochondria. Complementation of the primary structure of the complex. FEBS Lett. 313: 80-84, 1992. 2. Attardi, G., Chomyn, A., Doolittle, R. F., Mariottini, P., Ragan, C. I. Seven unidentified reading frames of human mitochondrial DNA encode subunits of the respiratory chain NADH dehydrogenase. Cold Spring Harbor Symp. Quant. Biol. 1: 103-114, 1986. 3. Attardi, G., Chomyn, A., Montoya, J., Ojala, D. Identification and mapping of human mitochondrial genes. Cytogenet. Cell Genet. 32: 85-98, 1982. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4)
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别名
- Mtnd4
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背景
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Synonyms: NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4, Mtnd4, mt-Nd4, Nd4
Tissue Specificity: Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.
Background: NADH-ubiquinone oxidoreductase chain 4 is a protein that in humans is encoded by the mitochondrial gene MT-ND4. The ND4 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variations in the MT-ND4 gene are associated with age-related macular degeneration (AMD), Leber's hereditary optic neuropathy (LHON), mesial temporal lobe epilepsy (MTLE) and cystic fibrosis.
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分子量
- 48 kDa
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基因ID
- 26201
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UniProt
- P05508
抗原
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