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MUT 抗体 (N-Term)

MUT 适用: 小鼠, 人, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 2D6 unconjugated
产品编号 ABIN7603112
发货至: 中国
  • 抗原 See all MUT 抗体
    MUT (Methylmalonyl Coenzyme A Mutase (MUT))
    抗原表位
    • 5
    • 4
    • 3
    • 2
    • 1
    N-Term
    适用
    • 14
    • 13
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠, 人, 大鼠
    宿主
    • 16
    • 3
    小鼠
    克隆类型
    • 16
    • 3
    单克隆
    标记
    • 15
    • 2
    • 1
    • 1
    This MUT antibody is un-conjugated
    应用范围
    • 14
    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Anti-Methylmalonyl Coenzyme A mutase Antibody Picoband® (monoclonal, 2D6)
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-Methylmalonyl Coenzyme A mutase Antibody Picoband® (monoclonal, 2D6) (ABIN7603112). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human MUT, different from the related mouse sequence by one amino acid.
    克隆位点
    2D6
    亚型
    IgG2b
    Top Product
    Discover our top product MUT Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
    1. Adjalla, C. E., Hosack, A. R., Gilfix, B. M., Lamothe, E., Sun, S., Chan, A., Evans, S., Matiaszuk, N. V., Rosenblatt, D. S. Seven novel mutations in mut methylmalonic aciduria. Hum. Mutat. 11: 270-274, 1998. 2. Berger, I., Shaag, A., Anikster, Y., Baumgartner, E. R., Bar-Meir, M., Joseph, A., Elpeleg, O. N. Mutation analysis of the MCM gene in Israeli patients with mut(0) disease. Molec. Genet. Metab. 73: 107-110, 2001. 3. Cavicchi, C., Donati, M. A., Funghini, S., la Marca, G., Malvagia, S., Ciani, F., Poggi, G. M., Pasquini, E., Zammarchi, E., Morrone, A. Genetic and biochemical approach to early prenatal diagnosis in a family with mut methylmalonic aciduria. Clin. Genet. 69: 72-76, 2006.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    MUT (Methylmalonyl Coenzyme A Mutase (MUT))
    别名
    MUT (MUT 产品)
    背景

    Synonyms: MCM, Mut

    Tissue Specificity: B-cells.

    Background: Methylmalonyl-CoA mutase (MUT) is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. This gene is mapped to 6p12.3. MUT requires a vitamin B12-derived prosthetic group, adenosylcobalamin (commonly referred to as AdoCbl), to function. And the product of this enzyme, succinyl-CoA, is a key molecule of the TCA cycle.

    分子量
    83 kDa
    基因ID
    4594
    UniProt
    P22033
    途径
    Monocarboxylic Acid Catabolic Process
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