GAP43 抗体 (N-Term)
Quick Overview for GAP43 抗体 (N-Term) (ABIN7603111)
抗原
See all GAP43 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-GAP43 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GAP43 Antibody Picoband® (ABIN7603111). Tested in Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human GAP43, which shares 95.2% amino acid (aa) sequence identity with both mouse and rat GAP43.
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亚型
- IgG
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anti-Growth Associated Protein 43 (GAP43) (AA 9-100) antibody
GAP43 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-274) antibodyGAP43 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-238) antibodyGAP43 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-238) antibodyGAP43 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-238) antibodyGAP43 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) antibodyGAP43 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (pSer41) antibodyGAP43 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) antibodyGAP43 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 8-226) antibodyGAP43 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) antibodyGAP43 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal Mix unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Rat
Immunofluorescence, 5 μg/mL, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Kosik, K. S., Orecchio, L. D., Bruns, G. A. P., Benowitz, L. I., MacDonald, G. P., Cox, D. R., Neve, R. L. Human GAP-43: its deduced amino acid sequence and chromosomal localization in mouse and human. Neuron 1: 127-132, 1988. 2. Reeves, R. H., O'Hara, B. F., Gearhart, J. D. Localization on mouse chromosome 16 of Smst and Gap43: a conserved synteny with human chromosome 3. (Abstract) Cytogenet. Cell Genet. 51: 1064, 1989. 3. Strittmatter, S. M., Fankhauser, C., Huang, P. L., Mashimo, H., Fishman, M. C. Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell 80: 445-452, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GAP43 (Growth Associated Protein 43 (GAP43))
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别名
- GAP43
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背景
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Synonyms: Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, pp46, GAP43
Tissue Specificity: Isoform 1 and isoform 2 are expressed in liver, colon and small intestine. Isoform 2 but not isoform 1 is expressed in kidney. Isoform 1 and isoform 2 are not expressed in esophagus. Not expressed in skin.
Background: Growth Associated Protein 43 (GAP43) is a protein encoded by the GAP43 gene in humans. It is mapped to 3q13.31. The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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分子量
- 38-43 kDa
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基因ID
- 2596
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UniProt
- P17677
抗原
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