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SATB2 抗体 (Middle Region)

This anti-SATB2 antibody is a 兔 多克隆 antibody detecting SATB2 in WB. Suitable for 人.
产品编号 ABIN7603086
发货至: 中国

Quick Overview for SATB2 抗体 (Middle Region) (ABIN7603086)

抗原

See all SATB2 抗体
SATB2 (SATB Homeobox 2 (SATB2))

适用

  • 66
  • 35
  • 30
  • 1
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  • 1

宿主

  • 58
  • 8

克隆类型

  • 43
  • 23
多克隆

标记

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  • 4
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  • 3
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  • 1
  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This SATB2 antibody is un-conjugated

应用范围

  • 45
  • 21
  • 15
  • 15
  • 13
  • 13
  • 9
  • 7
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 16
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-SATB2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SATB2 Antibody Picoband® (ABIN7603086). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human SATB2, identical to the related mouse sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    1. Bengani, H., Handley, M., Alvi, M., Ibitoye, R., Lees, M., Lynch, S. A., Lam, W., Fannemel, M., Nordgren, A., Malmgren, H., Kvarnung, M., Mehta, S., and 22 others. Clinical and molecular consequences of disease-associated de novo mutations in SATB2. Genet Med. 19: 900-908, 2017. 2. Brewer, C. M., Leek, J. P., Green, A. J., Holloway, S., Bonthron, D. T., Markham, A. F., FitzPatrick, D. R. A locus for isolated cleft palate, located on human chromosome 2q32. Am. J. Hum. Genet. 65: 387-396, 1999. 3. Britanova, O., Depew, M. J., Schwark, M., Thomas, B. L., Miletich, I., Sharpe, P., Tarabykin, V. Satb2 haploinsufficiency phenocopies 2q32-q33 deletions, whereas loss suggests a fundamental role in the coordination of jaw development. Am. J. Hum. Genet. 79: 668-678, 2006.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SATB2 (SATB Homeobox 2 (SATB2))

    别名

    SATB2

    背景

    Synonyms: Phospholipase D2, PLD 2, hPLD2, Choline phosphatase 2, PLD1C, Phosphatidylcholine-hydrolyzing phospholipase D2, PLD2

    Tissue Specificity: Widely expressed.

    Background: Special AT-rich sequence-binding protein 2 (SATB2) also known as DNA-binding protein SATB2 is a protein that in humans is encoded by the SATB2 gene. This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein.

    分子量

    90 kDa

    基因ID

    23314
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