IMPDH2 抗体 (Middle Region)
Quick Overview for IMPDH2 抗体 (Middle Region) (ABIN7603063)
抗原
See all IMPDH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-IMPDH2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IMPDH2 Antibody Picoband® (ABIN7603063). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human IMPDH2, identical to the related mouse and rat sequences.s
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亚型
- IgG
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anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 1-514) antibody
IMPDH2 适用: 人 WB, ELISA, IP, RNAi 宿主: 小鼠 Monoclonal 1E12-B6 unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 5-514) antibodyIMPDH2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) antibodyIMPDH2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) antibodyIMPDH2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) antibodyIMPDH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 215-514) antibodyIMPDH2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 1-514) antibodyIMPDH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 215-514) antibodyIMPDH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 215-514) antibodyIMPDH2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 180-210) antibodyIMPDH2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19383 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human
1. Glesne, D. A., Huberman, E. Cloning and sequencing of the human type II IMP dehydrogenase gene. Biochem. Biophys. Res. Commun. 205: 537-544, 1994. 2. Glesne, D., Collart, F., Varkony, T., Drabkin, H., Huberman, E. Chromosomal localization and structure of the human type II IMP dehydrogenase gene (IMPDH2). Genomics 16: 274-277, 1993. 3. Kost-Alimova, M. V., Glesne, D. A., Huberman, E., Zelenin, A. V. Assignment of inosine 5-prime-monophosphate dehydrogenase type 2 (IMPDH2) to human chromosome band 3p21.2 by in situ hybridization. Cytogenet. Cell Genet. 82: 145-146, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
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别名
- IMPDH2
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背景
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Synonyms: Myelin-associated glycoprotein, Siglec-4a, MAG, GMA
Tissue Specificity: Both isoform 1 and isoform 2 are detected in myelinated structures in the central and peripheral nervous system, in periaxonal myelin and at Schmidt-Lanterman incisures. Detected in optic nerve, in oligodendroglia and in periaxonal myelin sheaths. Detected in compact myelin (at protein level). Both isoform 1 and isoform 2 are detected in the central and peripheral nervous system
Background: Inosine-5'-monophosphate dehydrogenase 2, also known as IMP dehydrogenase 2, is an enzyme that in humans is encoded by the IMPDH2 gene. This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
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分子量
- 56 kDa
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基因ID
- 3615
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UniProt
- P12268
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途径
- Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
抗原
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