HSD17B3 抗体 (Middle Region)
Quick Overview for HSD17B3 抗体 (Middle Region) (ABIN7603060)
抗原
See all HSD17B3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-HSD17B3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HSD17B3 Antibody Picoband® (ABIN7603060). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human HSD17B3, which shares 68.4% amino acid (aa) sequence identity with rat HSD17B3.
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亚型
- IgG
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (AA 29-119) antibody
HSD17B3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (AA 1-310) antibodyHSD17B3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (AA 89-118) antibodyHSD17B3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24061 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (AA 96-126), (Middle Region) antibodyHSD17B3 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (AA 1-310) antibodyHSD17B3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (AA 51-100) antibodyHSD17B3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (AA 141-155) antibodyVerified HSD17B3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (N-Term) antibodyHSD17B3 适用: 人, 大鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Ademola Akesode, F., Meyer, W. J., III, Migeon, C. J. Male pseudohermaphroditism with gynaecomastia due to testicular 17-ketosteroid reductase deficiency. Clin. Endocr. 7: 443-452, 1977. 2. Andersson, S., Geissler, W. M., Wu, L., Davis, D. L., Grumbach, M. M., New, M. I., Schwarz, H. P., Blethen, S. L., Mendonca, B. B., Bloise, W., Witchel, S. F., Cutler, G. B., Jr., Griffin, J. E., Wilson, J. D., Russell, D. W. Molecular genetics and pathophysiology of 17-beta-hydroxysteroid dehydrogenase 3 deficiency. J. Clin. Endocr. Metab. 81: 130-136, 1996. 3. Bilbao, J. R., Loridan, L., Audi, L., Gonzalo, E., Castano, L. A novel missense (R80W) mutation in 17-beta-hydroxysteroid dehydrogenase type 3 gene associated with male pseudohermaphroditism. Europ. J. Endocr. 139: 330-333, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))
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别名
- HSD17B3
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背景
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Synonyms: Sodium channel protein type 11 subunit alpha, Peripheral nerve sodium channel 5, PN5, Sensory neuron sodium channel 2, Sodium channel protein type XI subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.9, hNaN, SCN11A, SCN12A, SNS2
Tissue Specificity: Expressed in the dorsal root ganglia and trigeminal ganglia, olfactory bulb, hippocampus, cerebellar cortex, spinal cord, spleen, small intestine and placenta.
Background: 17β-Hydroxysteroid dehydrogenase 3 (17β-HSD3) is an enzyme that in humans is encoded by the HSD17B3 gene and is involved in androgen steroidogenesis. This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
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分子量
- 40 kDa
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基因ID
- 3293
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UniProt
- P37058
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途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
抗原
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