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Orexin 抗体 (Middle Region)

OX 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7603056
发货至: 中国
  • 抗原 See all Orexin (OX) 抗体
    Orexin (OX)
    抗原表位
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 20
    • 14
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 16
    • 5
    克隆类型
    • 21
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Orexin antibody is un-conjugated
    应用范围
    • 9
    • 8
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    Anti-HCRT Antibody
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Anti-HCRT Antibody Picoband® (ABIN7603056). Tested in IF, IHC application. This antibody reacts with Mouse, Rat.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human HCRT, identical to the related mouse and rat sequences.
    亚型
    IgG
    Top Product
    Discover our top product OX Primary Antibody
  • 应用备注
    Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
    Immunofluorescence, 5 μg/mL, Mouse, Rat
    1. Adamantidis, A. R., Zhang, F., Aravanis, A. M., Deisseroth, K., de Lecea, L. Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature 450: 420-424, 2007. 2. Arii, J., Kanbayashi, T., Tanabe, Y., Sawaishi, Y., Kimura, S., Watanabe, A., Mishima, K., Hishikawa, Y., Shimizu, T., Nishino, S. CSF hypocretin-1 (orexin-A) levels in childhood narcolepsy and neurologic disorders. Neurology 63: 2440-2442, 2004. 3. Blouin, A. M., Thannickal, T. C., Worley, P. F., Baraban, J. M., Reti, I. M., Siegel, J. M. Narp immunostaining of human hypocretin (orexin) neurons: loss in narcolepsy. Neurology 65: 1189-1192, 2005.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    Orexin (OX)
    别名
    HCRT (OX 产品)
    背景

    Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

    Tissue Specificity: Expressed in all tissues.

    Background: This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.

    分子量
    100,150 kDa
    基因ID
    3060
    UniProt
    O43612
    途径
    Synaptic Membrane, Feeding Behaviour
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