Orexin 抗体 (Middle Region)
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- 抗原 See all Orexin (OX) 抗体
- Orexin (OX)
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抗原表位
- Middle Region
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Orexin antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- Anti-HCRT Antibody
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
- Anti-HCRT Antibody Picoband® (ABIN7603056). Tested in IF, IHC application. This antibody reacts with Mouse, Rat.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human HCRT, identical to the related mouse and rat sequences.
- 亚型
- IgG
- Top Product
- Discover our top product OX Primary Antibody
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- 应用备注
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Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
Immunofluorescence, 5 μg/mL, Mouse, Rat
1. Adamantidis, A. R., Zhang, F., Aravanis, A. M., Deisseroth, K., de Lecea, L. Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature 450: 420-424, 2007. 2. Arii, J., Kanbayashi, T., Tanabe, Y., Sawaishi, Y., Kimura, S., Watanabe, A., Mishima, K., Hishikawa, Y., Shimizu, T., Nishino, S. CSF hypocretin-1 (orexin-A) levels in childhood narcolepsy and neurologic disorders. Neurology 63: 2440-2442, 2004. 3. Blouin, A. M., Thannickal, T. C., Worley, P. F., Baraban, J. M., Reti, I. M., Siegel, J. M. Narp immunostaining of human hypocretin (orexin) neurons: loss in narcolepsy. Neurology 65: 1189-1192, 2005. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- Orexin (OX)
- 别名
- HCRT (OX 产品)
- 背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
- 分子量
- 100,150 kDa
- 基因ID
- 3060
- UniProt
- O43612
- 途径
- Synaptic Membrane, Feeding Behaviour
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