COX6A2 抗体 (Middle Region)
Quick Overview for COX6A2 抗体 (Middle Region) (ABIN7603039)
抗原
See all COX6A2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-Cox6a2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Cox6a2 Antibody Picoband® (ABIN7603039). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of mouse Cox6a2, which shares 66.7% and 100% amino acid (aa) sequence identity with human and rat Cox6a2, respectively.
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亚型
- IgG
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anti-Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2) (C-Term) antibody
COX6A2 适用: 人, 小鼠 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2) (AA 37-66) antibodyCOX6A2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB23260 unconjugated
anti-Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2) antibodyCOX6A2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
1. Bachman, N. J., Riggs, P. K., Siddiqui, N., Makris, G. J., Womack, J. E., Lomax, M. I. Structure of the human gene (COX6A2) for the heart/muscle isoform of cytochrome c oxidase subunit VIa and its chromosomal location in humans, mice, and cattle. Genomics 42: 146-151, 1997. 2. Inoue, M., Uchino, S., Iida, A., Noguchi, S., Hayashi, S., Takahashi, T., Fujii, K., Komaki, H., Takeshita, E., Nonaka, I., Okada, Y., Yoshizawa, T., Van Lommel, L., Schuit, F., Goto, Y., Mimaki, M., Nishino, I. COX6A2 variants cause a muscle-specific cytochrome c oxidase deficiency. Ann. Neurol. 86: 193-202, 2019. 3. Quintens, R., Singh, S., Lemaire, K., De Bock, K., Granvik, M., Schraenen, A., Vroegrijk, I. O. C. M., Costa, V., Van Noten, P., Lambrechts, D., Lehnert, S., Van Lommel, L., and 10 others. Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance. PLoS One 8: e56719, 2013. Note: Electronic Article. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- COX6A2 (Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2))
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别名
- Cox6a2
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背景
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Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: Cytochrome c oxidase subunit VIa polypeptide 2 is a protein that in humans is encoded by the COX6A2 gene. Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66 % amino acid sequence identity.
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分子量
- 11 kDa
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基因ID
- 12862
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UniProt
- P43023
抗原
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