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Cathepsin F 抗体 (Middle Region)

This anti-Cathepsin F antibody is a 兔 多克隆 antibody detecting Cathepsin F in WB, IHC 和 FACS. Suitable for 人.
产品编号 ABIN7603030
发货至: 中国
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Quick Overview for Cathepsin F 抗体 (Middle Region) (ABIN7603030)

抗原

See all Cathepsin F (CTSF) 抗体
Cathepsin F (CTSF)

适用

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宿主

  • 33
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克隆类型

  • 35
  • 2
多克隆

标记

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This Cathepsin F antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

    • 6
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    Middle Region

    原理

    Anti-Cathepsin F/CTSF Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Cathepsin F-CTSF Antibody (ABIN7603030). Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human Cathepsin F/CTSF, which shares 69.6% amino acid (aa) sequence identity with both mouse Cathepsin F/CTSF.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry, 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Cathepsin F (CTSF)

    别名

    CTSF

    背景

    Synonyms: CTSF, Cathepsin F, CATSF, EC 3.4.22.41

    Background: Cathepsin F is a protein that in humans is encoded by the CTSF gene. Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

    分子量

    53 kDa

    基因ID

    8722
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