BRD3 抗体 (Middle Region)
Quick Overview for BRD3 抗体 (Middle Region) (ABIN7603025)
抗原
See all BRD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-BRD3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-BRD3 Antibody Picoband® (ABIN7603025). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human BRD3, identical to the related mouse sequences.
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亚型
- IgG
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anti-Bromodomain Containing 3 (BRD3) (AA 418-556) antibody
BRD3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 7G6 unconjugated
anti-Bromodomain Containing 3 (BRD3) (AA 418-556) antibodyBRD3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6E7 unconjugated
anti-Bromodomain Containing 3 (BRD3) (C-Term) antibodyBRD3 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 3 (BRD3) (Middle Region) antibodyBRD3 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 兔, 斑马鱼, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 3 (BRD3) (C-Term) antibodyBRD3 适用: 人, 小鼠 WB, ChIP-seq, ChIP, CUT&RUN 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 3 (BRD3) antibodyBRD3 适用: 人 WB, IP, ICC, FACS, DB 宿主: 小鼠 Monoclonal 2088C3a unconjugated
anti-Bromodomain Containing 3 (BRD3) (C-Term) antibodyBRD3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 3 (BRD3) (AA 356-506) antibodyBRD3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 3 (BRD3) antibodyBRD3 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 3 (BRD3) (AA 1-556) antibodyBRD3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Dawson, M. A., Prinjha, R. K., Dittmann, A., Giotopoulos, G., Bantscheff, M., Chan, W.-I., Robson, S. C., Chung, C., Hopf, C., Savitski, M. M., Huthmacher, C., Gudgin, E., and 15 others. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature 478: 529-533, 2011. 2. Nomura, N., Nagase, T., Miyajima, N., Sazuka, T., Tanaka, A., Sato, S., Seki, N., Kawarabayasi, Y., Ishikawa, K., Tabata, S. Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 1: 223-229, 1994. 3. Thorpe, K. L., Abdulla, S., Kaufman, J., Trowsdale, J., Beck, S. Phylogeny and structure of the RING3 gene. Immunogenetics 44: 391-396, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- BRD3 (Bromodomain Containing 3 (BRD3))
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别名
- BRD3
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背景
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Synonyms: Myogenic factor 5, Myf-5, Class C basic helix-loop-helix protein 2, bHLHc2, MYF5, BHLHC2
Tissue Specificity: Ubiquitously expressed. Present at highest levels in the brain, at high levels in the placenta and testis, at intermediate levels in the intestine, ovary, skeletal muscle and thymus and at lower levels in heart, kidney, liver, lung, pancreas, prostate and spleen. In the kidney, it is widely expressed in tubules, but sparsely expressed in the glomerulus (PubMed:24676636). Expression is significantly increased in renal biopsy specimens from idiopathic FSGS (PubMed:24676636). Overexpressed in many tumor types including breast, colorectal, endometrial, hepatic, kidney, lung, ovarian and pancreatic tumors.
Background: Bromodomain-containing protein 3 (BRD3) also known as RING3-like protein (RING3L) is a protein that in humans is encoded by the BRD3 gene. This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.
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分子量
- 80 kDa
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基因ID
- 8019
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UniProt
- Q15059
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途径
- Chromatin Binding
抗原
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