BMPR1A 抗体 (Middle Region)
Quick Overview for BMPR1A 抗体 (Middle Region) (ABIN7603023)
抗原
See all BMPR1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-BMPR1A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-BMPR1A Antibody Picoband® (ABIN7603023). Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human BMPR1A, which shares 95.8% amino acid (aa) sequence identity with mouse BMPR1A.
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亚型
- IgG
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anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 179-378) antibody
BMPR1A 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4B7B2 unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 101-200) antibodyBMPR1A 适用: 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 30-60) antibodyBMPR1A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 177-532) antibodyBMPR1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (N-Term) antibodyBMPR1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 24-200) antibodyBMPR1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 30-60), (N-Term) antibodyBMPR1A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01766 unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 21-51) antibodyBMPR1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 166-195) antibodyBMPR1A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB05263 unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 166-196), (C-Term) antibodyBMPR1A 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01772 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Astrom, A.-K., Jin, D., Imamura, T., Roijer, E., Rosenzweig, B., Miyazono, K., ten Dijke, P., Stenman, G. Chromosomal localization of three human genes encoding bone morphogenetic protein receptors. Mammalian Genome 10: 299-302, 1999. 2. Cao, X., Eu, K. W., Kumarasinghe, M. P., Li, H. H., Loi, C., Cheah, P. Y. Mapping of hereditary mixed polyposis syndrome (HMPS) to chromosome 10q23 by genomewide high-density single nucleotide polymorphism (SNP) scan and identification of BMPR1A loss of function. J. Med. Genet. 43: e13, 2006. Note: Electronic Article. 3. Cejalvo, T., Sacedon, R., Hernandez-Lopez, C., Diez, B., Gutierrez-Frias, C., Valencia, J., Zapata, A. G., Varas, A., Vicente, A. Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development. Immunology 121: 94-104, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
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别名
- BMPR1A
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背景
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Synonyms: BMPR1A, ACVRLK3, ALK3, Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, EC 2.7.11.30, Activin receptor-like kinase 3, ALK-3, Serine/threonine-protein kinase receptor R5, SKR5, CD antigen CD292
Background: The bone morphogenetic protein receptor, type IA also known as BMPR1A is a protein which in humans is encoded by the BMPR1A gene. The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
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分子量
- 60 kDa
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基因ID
- 657
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UniProt
- P36894
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途径
- Stem Cell Maintenance
抗原
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