PNP 抗体 (Middle Region)
Quick Overview for PNP 抗体 (Middle Region) (ABIN7602997)
抗原
See all PNP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Middle Region
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原理
- Anti-PNP Antibody Picoband® (monoclonal, 7G5)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PNP Antibody Picoband® (monoclonal, 7G5) (ABIN7602997). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PNP, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.
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亚型
- IgG2b
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anti-Purine Nucleoside Phosphorylase (PNP) (AA 161-189) antibody
PNP 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 161-189), (Middle Region) antibodyPNP 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E5 unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 174-283) antibodyPNP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 142-153) antibodyVerified PNP 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 68-289) antibodyPNP 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 145-178) antibodyPNP 适用: 人 WB 宿主: 兔 Polyclonal RB49601 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. Williams, S. R., Goddard, J. M., Martin, D. W., Jr. Human purine nucleoside phosphorylase cDNA sequence and genomic clone characterization. Nucleic Acids Res. 12: 5779-5787, 1984. 2. Frecker, M., Dallaire, L., Young, S. R., Chen, G. C. C., Simpson, N. E. Confirmation of regional assignment of nucleoside phosphorylase (NP) on chromosome 14 by gene dosage studies. Hum. Genet. 45: 167-173, 1978. 3. Markert, M. L., Finkel, B. D., McLaughlin, T. M., Watson, T. J., Collard, H. R., McMahon, C. P., Andrews, L. G., Barrett, M. J., Ward, F. E. Mutations in purine nucleoside phosphorylase deficiency. Hum. Mutat. 9: 118-121, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PNP (Purine Nucleoside Phosphorylase (PNP))
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别名
- PNP
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背景
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Synonyms: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, CLPX
Tissue Specificity: Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas.
Background: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised Tlymphocyte function and neurologic dysfunction.
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分子量
- 32 kDa
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基因ID
- 4860
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UniProt
- P00491
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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