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PNP 抗体 (Middle Region)

This anti-PNP antibody is a 小鼠单克隆 antibody detecting PNP in WB. Suitable for 人和大鼠.

产品编号 ABIN7602996

发货至: 中国

Datasheet as PDF

Quick Overview for PNP 抗体 (Middle Region) (ABIN7602996)

抗原

See all PNP 抗体

PNP (Purine Nucleoside Phosphorylase (PNP))

适用

34
7
7
3
1
1
1
1
1
1
1
1

人, 大鼠

宿主

小鼠

克隆类型

单克隆

标记

32
3
3
1
1
1
1
1
1

This PNP antibody is un-conjugated

应用范围

32
19
18
16
10
9
7
3
2
2
1
1
1
1
1

Western Blotting (WB)

克隆位点

2H10

Discover our top product PNP Primary Antibody

抗原表位
20

4

4

2

1

1

1

1

1

1

1

1
Middle Region

原理

Anti-PNP Antibody Picoband® (monoclonal, 2H10)

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-PNP Antibody Picoband® (monoclonal, 2H10) (ABIN7602996). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human PNP, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.

亚型

IgG2b
anti-Purine Nucleoside Phosphorylase (PNP) (AA 161-189) antibody
PNP 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Purine Nucleoside Phosphorylase (PNP) (AA 161-189), (Middle Region) antibody
PNP 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibody
PNP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E5 unconjugated

anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibody
PNP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibody
PNP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Purine Nucleoside Phosphorylase (PNP) (AA 174-283) antibody
PNP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Purine Nucleoside Phosphorylase (PNP) (AA 142-153) antibody
Verified PNP 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Purine Nucleoside Phosphorylase (PNP) (AA 68-289) antibody
PNP 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated

anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibody
PNP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Purine Nucleoside Phosphorylase (PNP) (AA 145-178) antibody
PNP 适用: 人 WB 宿主: 兔 Polyclonal RB49601 unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human, Rat
1. Williams, S. R., Goddard, J. M., Martin, D. W., Jr. Human purine nucleoside phosphorylase cDNA sequence and genomic clone characterization. Nucleic Acids Res. 12: 5779-5787, 1984. 2. Frecker, M., Dallaire, L., Young, S. R., Chen, G. C. C., Simpson, N. E. Confirmation of regional assignment of nucleoside phosphorylase (NP) on chromosome 14 by gene dosage studies. Hum. Genet. 45: 167-173, 1978. 3. Markert, M. L., Finkel, B. D., McLaughlin, T. M., Watson, T. J., Collard, H. R., McMahon, C. P., Andrews, L. G., Barrett, M. J., Ward, F. E. Mutations in purine nucleoside phosphorylase deficiency. Hum. Mutat. 9: 118-121, 1997.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

PNP (Purine Nucleoside Phosphorylase (PNP))

别名

PNP

背景

Synonyms: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, CLPX
Tissue Specificity: Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas.
Background: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised Tlymphocyte function and neurologic dysfunction.

分子量

32 kDa

基因ID

4860

UniProt

P00491

途径

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus

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