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PNP 抗体 (Middle Region)

This 小鼠 单克隆 antibody specifically detects PNP in WB. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN7602996
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PNP 抗体 (Middle Region) (ABIN7602996)

抗原

See all PNP 抗体
PNP (Purine Nucleoside Phosphorylase (PNP))

适用

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人, 大鼠

宿主

  • 31
  • 6
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小鼠

克隆类型

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  • 6
单克隆

标记

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This PNP antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

2H10
  • 抗原表位

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    Middle Region

    原理

    Anti-PNP Antibody (monoclonal, 2H10)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PNP Antibody (monoclonal, 2H10) (ABIN7602996). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human PNP, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    PNP (Purine Nucleoside Phosphorylase (PNP))

    别名

    PNP

    背景

    Synonyms: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, CLPX

    Tissue Specificity: Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas.

    Background: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised Tlymphocyte function and neurologic dysfunction.

    分子量

    32 kDa

    基因ID

    4860

    UniProt

    P00491

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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