Fibrinogen beta Chain 抗体 (Middle Region)
Quick Overview for Fibrinogen beta Chain 抗体 (Middle Region) (ABIN7602994)
抗原
See all Fibrinogen beta Chain (FGB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Middle Region
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原理
- Anti-Fibrinogen beta chain/FGB Antibody Picoband® (monoclonal, 6D12)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Fibrinogen beta chain/FGB Antibody Picoband® (monoclonal, 6D12) (ABIN7602994). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human FGB, different from the related mouse sequence by three amino acids, and from the related rat sequence by five amino acids.
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亚型
- IgG2b
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anti-Fibrinogen beta Chain (FGB) (AA 29-491) antibody
FGB 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen beta Chain (FGB) (AA 35-481) antibodyFGB 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen beta Chain (FGB) (AA 45-491) antibodyFGB 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Fibrinogen beta Chain (FGB) antibodyFGB 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen beta Chain (FGB) (AA 49-495) antibodyFGB 适用: Cow WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen beta Chain (FGB) (AA 29-118) antibodyFGB 适用: 人 WB, ELISA, ICC, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen beta Chain (FGB) (AA 392-491) antibodyFGB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Fibrinogen beta Chain (FGB) (AA 177-190) antibodyVerified FGB 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Fibrinogen beta Chain (FGB) (AA 202-491) antibodyFGB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen beta Chain (FGB) (AA 33-479) antibodyFGB 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
1. "Entrez Gene: FGB fibrinogen beta chain". 2. Chung, D. W., Que, B. G., Rixon, M. W., Mace, M., Jr., Davie, E. W. Characterization of complementary deoxyribonucleic acid and genomic deoxyribonucleic acid for the beta chain of human fibrinogen. Biochemistry 22: 3244-3250, 1983. 3. Spena, S., Duga, S., Asselta, R., Malcovati, M., Peyvandi, F., Tenchini, M. L. Congenital afibrinogenemia: first identification of splicing mutations in the fibrinogen B-beta-chain gene causing activation of cryptic splice sites. Blood 100: 4478-4484, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Fibrinogen beta Chain (FGB)
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别名
- FGB
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背景
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Synonyms: Bis (5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Fragile histidine triad protein, FHIT
Tissue Specificity: Low levels expressed in all tissues tested. Phospho-FHIT observed in liver and kidney, but not in brain and lung. Phospho-FHIT undetected in all tested human tumor cell lines.
Background: Fibrinogen beta chain, mapped to 4q31.3, is also known asFGB. The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 56 kDa
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基因ID
- 2244
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UniProt
- P02675
抗原
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