BCAM 抗体 (Middle Region)
Quick Overview for BCAM 抗体 (Middle Region) (ABIN7602976)
抗原
See all BCAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-CD239/BCAM Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-/BCAM Antibody (ABIN7602976). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human CD239/BCAM, which shares 84.4% amino acid (aa) sequence identity with both mouse and rat CD239/BCAM.
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亚型
- IgG
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anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) (AA 32-257) antibody
BCAM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) (AA 32-197) antibodyBCAM 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8C4E6 unconjugated
anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) (AA 447-547) antibodyBCAM 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) antibodyBCAM 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) (AA 32-131) antibodyBCAM 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) (C-Term) antibodyBCAM 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) (AA 459-508) antibodyBCAM 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) antibodyBCAM 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) (Internal Region) antibodyBCAM 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Campbell, I. G., Foulkes, W. D., Senger, G., Trowsdale, J., Garin-Chesa, P., Rettig, W. J. Molecular cloning of the B-CAM cell surface glycoprotein of epithelial cancers: a novel member of the immunoglobulin superfamily. Cancer Res. 54: 5761-5765, 1994. 2. Cook, P. J. L. The Lutheran-secretor recombination fraction in man: a possible sex difference. Ann. Hum. Genet. 28: 393-401, 1965. 3. Daniels, G. L., Le Pennec, P. Y., Rouger, P., Salmon, C., Tippett, P. The red cell antigens Au(a) and Au(b) belong to the Lutheran system. Vox Sang. 60: 191-192, 1991. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))
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别名
- BCAM
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背景
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Synonyms: Basal cell adhesion molecule, Auberger B antigen, B-CAM cell surface glycoprotein, F8/G253 antigen, Lutheran antigen, Lutheran blood group glycoprotein, CD239, BCAM, LU, MSK19
Tissue Specificity: Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
Background: Basal cell adhesion molecule, also known as Lutheran antigen, is a plasma membraneglycoprotein that in humans is encoded by the BCAM gene. It is mapped to 19q13.32. This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu (a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 70 kDa
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基因ID
- 4059
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UniProt
- P50895
抗原
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