RAN 抗体 (Cytosolic)
Quick Overview for RAN 抗体 (Cytosolic) (ABIN7602954)
抗原
See all RAN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Cytosolic
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原理
- Anti-Ran Monoclonal Antibody
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产品特性
- Anti-Ran Monoclonal Antibody (ABIN7602954). Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human Ran GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity) .
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亚型
- IgG
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应用备注
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WB 1:500-1:2000
ICC/IF 1:50-1:200
IP 1:50
FC 1:100 -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- RAN (RAN, Member RAS Oncogene Family (RAN))
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别名
- RAN
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背景
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Synonyms: Fibroblast growth factor receptor 3,FGFR-3,2.7.10.1,CD333,FGFR3,JTK4,
Tissue Specificity: Expressed in brain, kidney and testis. Very low or no expression in spleen, heart, and muscle. In 20- to 22- week old fetuses it is expressed at high level in kidney, lung, small intestine and brain, and to a lower degree in spleen, liver, and muscle. Isoform 2 is detected in epithelial cells. Isoform 1 is not detected in epithelial cells. Isoform 1 and isoform 2 are detected in fibroblastic cells. .
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分子量
- 103 kDa
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UniProt
- P62826
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途径
- Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus
抗原
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