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14-3-3 eta 抗体 (C-Term)

This anti-14-3-3 eta antibody is a 兔 多克隆 antibody detecting 14-3-3 eta in WB, IF, IHC, ICC 和 FACS. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7602945
发货至: 中国

Quick Overview for 14-3-3 eta 抗体 (C-Term) (ABIN7602945)

抗原

See all 14-3-3 eta (YWHAH) 抗体
14-3-3 eta (YWHAH)

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This 14-3-3 eta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-YWHAH Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-YWHAH Antibody Picoband® (ABIN7602945). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human YWHAH.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Ichimura-Ohshima, Y., Morii, K., Ichimura, T., Araki, K., Takahashi, Y., Isobe, T., Minoshima, S., Fukuyama, R., Shimizu, N., Kuwano, R. cDNA cloning and chromosome assignment of the gene for human brain 14-3-3 protein eta chain. J. Neurosci. Res. 31: 600-605, 1992. 2. Muratake, T., Hayashi, S., Ichikawa, T., Kumanishi, T., Ichimura, Y., Kuwano, R., Isobe, T., Wang, Y., Minoshima, S., Shimizu, N., Takahashi, Y. Structural organization and chromosomal assignment of the human 14-3-3-eta chain gene (YWHAH). Genomics 36: 63-69, 1996. 3. Park, E., Rawson, S., Li, K., Kim, B.-W., Ficarro, S. B., Gonzalez-Del Pino, G., Sharif, H., Marto, J. A., Jeon, H., Eck, M. J. Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature 575: 545-550, 2019.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    14-3-3 eta (YWHAH)

    别名

    YWHAH

    背景

    Synonyms: YWHAH, YWHA1, 14-3-3 protein eta, Protein AS1

    Background: 14-3-3 protein eta also referred to as 14-3-3η is a protein that in humans is encoded by the YWHAH gene. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.

    分子量

    28 kDa

    基因ID

    7533

    UniProt

    Q04917

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction
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