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S100A14 抗体 (C-Term)

S100A14 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7602920
发货至: 中国
  • 抗原 See all S100A14 抗体
    S100A14 (S100 Calcium Binding Protein A14 (S100A14))
    抗原表位
    • 8
    • 2
    • 1
    • 1
    C-Term
    适用
    • 22
    • 2
    • 2
    宿主
    • 18
    • 4
    克隆类型
    • 19
    • 2
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This S100A14 antibody is un-conjugated
    应用范围
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    原理
    Anti-S100A14 Antibody
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-A14 Antibody Picoband® (ABIN7602920). Tested in IHC applications. This antibody reacts with Human.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human S100A14, which shares 93.8% amino acid (aa) sequence identity with mouse S100A14.
    亚型
    IgG
    Top Product
    Discover our top product S100A14 Primary Antibody
  • 应用备注
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    1. Adam, P. J., Boyd, R., Tyson, K. L., Fletcher, G. C., Stamps, A., Hudson, L., Poyser, H. R., Redpath, N., Griffiths, M., Steers, G., Harris, A. L., Patel, S., Berry, J., Loader, J. A., Townsend, R. R., Daviet, L., Legrain, P., Parekh, R., Terrett, J. A. Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer. J. Biol. Chem. 278: 6482-6489, 2003. 2. Chen, H., Yu, D., Luo, A., Tan, W., Zhang, C., Zhao, D., Yang, M., Liu, J., Lin, D., Liu, Z. Functional role of S100A14 genetic variants and their association with esophageal squamous cell carcinoma. Cancer Res. 69: 3451-3457, 2009. 3. Pietas, A., Schluns, K., Marenholz, I., Schafer, B. W., Heizmann, C. W., Petersen, I. Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family. Genomics 79: 513-522, 2002.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    S100A14 (S100 Calcium Binding Protein A14 (S100A14))
    别名
    S100A14 (S100A14 产品)
    背景

    Synonyms: ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB

    Tissue Specificity: Brain, neural-specific.

    Background: S100 calcium binding protein A14 (S100A14) is a protein that in humans is encoded by the S100A14 gene. This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function.

    分子量
    18 kDa
    基因ID
    57402
    途径
    Activation of Innate immune Response, S100 Proteins
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