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S100A12 抗体 (C-Term)

This anti-S100A12 antibody is a 兔 多克隆 antibody detecting S100A12 in IHC. Suitable for 人.
产品编号 ABIN7602919
发货至: 中国

Quick Overview for S100A12 抗体 (C-Term) (ABIN7602919)

抗原

See all S100A12 抗体
S100A12 (S100 Calcium Binding Protein A12 (S100A12))

适用

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宿主

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克隆类型

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多克隆

标记

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This S100A12 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    原理

    Anti-S100A12 Antibody

    交叉反应 (详细)

    No cross reactivity with other proteins.

    产品特性

    Anti-A12 Antibody Picoband® (ABIN7602919). Tested in IHC application. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human S100A12.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry, 1-2 μg/mL, Human
    1. Cole, A. M., Kim, Y.-H., Tahk, S., Hong, T., Weis, P., Waring, A. J., Ganz, T. Calcitermin, a novel antimicrobial peptide isolated from human airway secretions. FEBS Lett. 504: 5-10, 2001. 2. Guignard, F., Mauel, J., Markert, M. Identification and characterization of a novel human neutrophil protein related to the S100 family. Biochem. J. 309: 395-401, 1995. 3. Hofmann, M. A., Drury, S., Fu, C., Qu, W., Taguchi, A., Lu, Y., Avila, C., Kambham, N., Bierhaus, A., Nawroth, P., Neurath, M. F., Slattery, T., Beach, D., McClary, J., Nagashima, M., Morser, J., Stern, D., Schmidt, A. M. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 97: 889-901, 1999.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    S100A12 (S100 Calcium Binding Protein A12 (S100A12))

    别名

    S100A12

    背景

    Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

    Tissue Specificity: Expressed in all tissues.

    Background: S100 calcium-binding protein A12 (S100A12) is a protein that in humans is encoded by the S100A12 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

    分子量

    56,60 kDa

    基因ID

    6283

    UniProt

    P80511

    途径

    Toll-Like Receptors Cascades, S100 Proteins
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