PACAP 抗体 (C-Term)
Quick Overview for PACAP 抗体 (C-Term) (ABIN7602909)
抗原
See all PACAP (ADCYAP1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-PACAP-38/ADCYAP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PACAP-38/ADCYAP1 Antibody Picoband® (ABIN7602909). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PACAP-38/ADCYAP1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 17-176) antibody
ADCYAP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 148-176), (C-Term) antibodyADCYAP1 适用: 人 WB, IHC (p), FACS, IF 宿主: 兔 Polyclonal RB21605 unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 1-175) antibodyADCYAP1 适用: 小鼠 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 1-175) antibodyADCYAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) antibodyADCYAP1 适用: 人 WB 宿主: 小鼠 Monoclonal 1996CT329-45-62 unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (C-Term) antibodyVerified ADCYAP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Dorus, S., Vallender, E. J., Evans, P. D., Anderson, J. R., Gilbert, S. L., Mahowald, M., Wyckoff, G. J., Malcom, C. M., Lahn, B. T. Accelerated evolution of nervous system genes in the origin of Homo sapiens. Cell 119: 1027-1040, 2004. 2. Freson, K., Hashimoto, H., Thys, C., Wittevrongel, C., Danloy, S., Morita, Y., Shintani, N., Tomiyama, Y., Vermylen, J., Hoylaerts, M. F., Baba, A., Van Geet, C. The pituitary adenylate cyclase-activating polypeptide is a physiological inhibitor of platelet activation. J. Clin. Invest. 113: 905-912, 2004. 3. Hamelink, C., Tjurmina, O., Damadzic, R., Young, W. S., Weihe, E., Lee, H.-W., Eiden, L. E. Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis. Proc. Nat. Acad. Sci. 99: 461-466, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))
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别名
- ADCYAP1
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背景
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Synonyms: Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2, FGF10
Tissue Specificity: Expressed in numerous tissues with highest level in testis.
Background: Pituitary adenylate cyclase-activating polypeptide also known as PACAP is a protein that in humans is encoded by the ADCYAP1 gene. This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants.
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分子量
- 19 kDa
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基因ID
- 116
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UniProt
- P18509
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途径
- Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Activity, cAMP Metabolic Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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