P2RY6 抗体 (C-Term)
Quick Overview for P2RY6 抗体 (C-Term) (ABIN7602907)
抗原
See all P2RY6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-P2Y6/P2RY6 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-P2Y6/P2RY6 Antibody Picoband® (ABIN7602907). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminusof human P2Y6/P2RY6, which shares 94.4% amino acid (aa) sequence identity with rat P2RY6.
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亚型
- IgG
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anti-Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) (C-Term) antibody
P2RY6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) (AA 172-186), (Extracellular) antibodyP2RY6 适用: 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) (C-Term) antibodyP2RY6 适用: 人, 猴 IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) (Cytoplasmic Domain) antibodyP2RY6 适用: 人, 大鼠, Cow, Pig, 兔, 猴, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) (AA 109-158) antibodyP2RY6 适用: 人, 大鼠, Cow, Pig, 兔, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) (AA 311-328), (Intracellular) antibodyKO Validated P2RY6 适用: 大鼠 WB, IHC, FACS, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) (AA 172-186), (Extracellular) antibody (FITC)P2RY6 适用: 小鼠 FACS, LCI 宿主: 兔 Polyclonal FITC
anti-Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) (AA 172-186), (Extracellular) antibody (PE)P2RY6 适用: 小鼠 FACS, LCI 宿主: 兔 Polyclonal PE
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
1. Chang, K., Hanaoka, K., Kumada, M., Takuwa, Y. Molecular cloning and functional analysis of a novel P2 nucleotide receptor. J. Biol. Chem. 270: 26152-26158, 1995. 2. Communi, D., Parmentier, M., Boeynaems, J.-M. Cloning, functional expression and tissue distribution of the human P2Y6 receptor. Biochem. Biophys. Res. Commun. 222: 303-308, 1996. 3. Giannattasio, G., Ohta, S., Boyce, J. R., Xing, W., Balestrieri, B., Boyce, J. A. The purinergic G protein-coupled receptor 6 inhibits effector T cell activation in allergic pulmonary inflammation. J. Immun. 187: 1486-1495, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- P2RY6 (Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6))
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别名
- P2RY6
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背景
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Synonyms: Protein NDRG3,N-myc downstream-regulated gene 3 protein,NDRG3,
Tissue Specificity: Ubiquitous. Highly expressed in brain. .
Background: P2Y purinoceptor 6 is a protein that in humans is encoded by the P2RY6 gene. The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
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分子量
- 45 kDa
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基因ID
- 5031
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UniProt
- Q15077
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途径
- Smooth Muscle Cell Migration
抗原
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