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MYL3/CMLC1 抗体 (C-Term)

This anti-MYL3/CMLC1 antibody is a 兔 多克隆 antibody detecting MYL3/CMLC1 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602904
发货至: 中国

Quick Overview for MYL3/CMLC1 抗体 (C-Term) (ABIN7602904)

抗原

See all MYL3/CMLC1 (MYL3) 抗体
MYL3/CMLC1 (MYL3) (Myosin, Light Chain 3 (MYL3))

适用

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人, 小鼠, 大鼠

宿主

  • 38
  • 6

克隆类型

  • 39
  • 4
多克隆

标记

  • 32
  • 2
  • 1
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This MYL3/CMLC1 antibody is un-conjugated

应用范围

  • 36
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Western Blotting (WB)
  • 抗原表位

    • 9
    • 6
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    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    C-Term

    原理

    Anti-MYL3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-MYL3 Antibody Picoband® (ABIN7602904). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human MYL3, which shares 91.3% amino acid (aa) sequence identity with both mouse and rat MYL3.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    1. Arad, M., Penas-Lado, M., Monserrat, L., Maron, B. J., Sherrid, M., Ho, C. Y., Barr, S., Karim, A., Olson, T. M., Kamisago, M., Seidman, J. G., Seidman, C. E. Gene mutations in apical hypertrophic cardiomyopathy. Circulation 112: 2805-2811, 2005. 2. Caleshu, C., Sakhuja, R., Nussbaum, R. L., Schiller, N. B., Ursell, P. C., Eng, C., De Marco, T., McGlothlin, D., Burchard, E. G., Rame, J. E. Furthering the link between the sarcomere and primary cardiomyopathies: restrictive cardiomyopathy associated with multiple mutations in genes previously associated with hypertrophic or dilated cardiomyopathy. Am. J. Med. Genet. 155A: 2229-2235, 2011. 3. Cohen-Haguenauer, O., Barton, P. J. R., Van Cong, N., Cohen, A., Masset, M., Buckingham, M., Frezal, J. Chromosomal assignment of two myosin alkali light-chain genes encoding the ventricular/slow skeletal muscle isoform and the atrial/fetal muscle isoform (MYL3, MYL4). Hum. Genet. 81: 278-282, 1989.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    MYL3/CMLC1 (MYL3) (Myosin, Light Chain 3 (MYL3))

    别名

    MYL3

    背景

    Synonyms: MYL3, Myosin light chain 3, Cardiac myosin light chain 1, CMLC1, Myosin light chain 1, slow-twitch muscle B/ventricular isoform, MLC1SB, Ventricular myosin alkali light chain, Ventricular myosin light chain 1, VLCl, Ventricular/slow twitch myosin alkali light chain, MLC-lV/sb

    Background: Myosin essential light chain (ELC), ventricular/cardiac isoform is a protein that in humans is encoded by the MYL3 gene. MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.

    分子量

    25 kDa

    基因ID

    4634

    UniProt

    P08590
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