GPR161 抗体 (C-Term)
Quick Overview for GPR161 抗体 (C-Term) (ABIN7602890)
抗原
See all GPR161 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-GPR161 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-G Antibody Picoband® (ABIN7602890). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human GPR161, identical to the related mouse sequences.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
1. Gross, M. B. Personal Communication. Baltimore, Md. 9/30/2015. 2. Karaca, E., Buyukkaya, R., Pehlivan, D., Charng, W.-L., Yaykasli, K. O., Bayram, Y., Gambin, T., Withers, M., Atik, M. M., Arslanoglu, I., Bolu, S., Erdin, S., Buyukkaya, A., Yaykasli, E., Jhangiani, S. N., Muzny, D. M., Gibbs, R. A., Lupski, J. R. Whole-exome sequencing identifies homozygous GPR161 mutation in a family with pituitary stalk interruption syndrome. J. Clin. Endocr. Metab. 100: E140-E147, 2015. Note: Electronic Article. 3. Matteson, P. G., Desai, J., Korstanje, R., Lazar, G., Borsuk, T. E., Rollins, J., Kadambi, S., Joseph, J., Rahman, T., Wink, J., Benayed, R., Paigen, B., Millonig, J. H. The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development. Proc. Nat. Acad. Sci. 105: 2088-2093, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
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别名
- GPR161
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背景
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Synonyms: Neutrophil defensin 1,Defensin, alpha 1,HNP-1,HP-1,HP1,HP 1-56,Neutrophil defensin 2,HNP-2,HP-2,HP2,DEFA1,DEF1, DEFA2, MRS,DEFA1B,
Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.
Background: G-protein coupled receptor 161 is a protein that in humans is encoded by the GPR161 gene. The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer.
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分子量
- 60 kDa
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基因ID
- 23432
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UniProt
- Q8N6U8
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途径
- cAMP Metabolic Process
抗原
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