GFPT1 抗体 (C-Term)
Quick Overview for GFPT1 抗体 (C-Term) (ABIN7602887)
抗原
See all GFPT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-GFPT1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-GFPT1 Antibody Picoband® (ABIN7602887). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human GFPT1, identical to the related mouse and rat sequences.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Rat
1. Helman, G., Sharma, S., Crawford, J., Patra, B., Jain, P., Bent, S. J., Urtizberea, J. A., Saran, R. K., Taft, R. J., van der Knaap, M. S., Simons, C. Leukoencephalopathy due to variants in GFPT1-associated congenital myasthenic syndrome. Neurology 92: e587-e593, 2019. Note: Electronic Article. 2. Issop, Y., Hathazi, D., Khan, M. M., Rudolf, R., Weis, J., Spendiff, S., Slater, C. R., Roos, A., Lochmuller, H. GFPT1 deficiency in muscle leads to myasthenia and myopathy in mice. Hum. Molec. Genet. 27: 3218-3232, 2018. 3. McKnight, G. L., Mudri, S. L., Mathewes, S. L., Traxinger, R. R., Marshall, S., Sheppard, P. O., O'Hara, P. J. Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase. J. Biol. Chem. 267: 25208-25212, 1992. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GFPT1 (Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1))
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别名
- GFPT1
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背景
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Synonyms: Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA, IL3R
Tissue Specificity: Brain.
Background: Glucosamine-fructose-6-phosphate aminotransferase isomerizing 1 is an enzyme that in humans is encoded by the GFPT1 gene. This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate.
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分子量
- 79 kDa
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基因ID
- 2673
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UniProt
- Q06210
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途径
- ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process
抗原
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