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GFPT1 抗体 (C-Term)

This anti-GFPT1 antibody is a 兔 多克隆 antibody detecting GFPT1 in WB, IHC, IF, ICC 和 FACS. Suitable for 人 和 大鼠.
产品编号 ABIN7602887
发货至: 中国

Quick Overview for GFPT1 抗体 (C-Term) (ABIN7602887)

抗原

See all GFPT1 抗体
GFPT1 (Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1))

适用

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人, 大鼠

宿主

  • 34
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克隆类型

  • 31
  • 5
多克隆

标记

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This GFPT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 6
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    • 1
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    C-Term

    原理

    Anti-GFPT1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-GFPT1 Antibody Picoband® (ABIN7602887). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human GFPT1, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Rat
    1. Helman, G., Sharma, S., Crawford, J., Patra, B., Jain, P., Bent, S. J., Urtizberea, J. A., Saran, R. K., Taft, R. J., van der Knaap, M. S., Simons, C. Leukoencephalopathy due to variants in GFPT1-associated congenital myasthenic syndrome. Neurology 92: e587-e593, 2019. Note: Electronic Article. 2. Issop, Y., Hathazi, D., Khan, M. M., Rudolf, R., Weis, J., Spendiff, S., Slater, C. R., Roos, A., Lochmuller, H. GFPT1 deficiency in muscle leads to myasthenia and myopathy in mice. Hum. Molec. Genet. 27: 3218-3232, 2018. 3. McKnight, G. L., Mudri, S. L., Mathewes, S. L., Traxinger, R. R., Marshall, S., Sheppard, P. O., O'Hara, P. J. Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase. J. Biol. Chem. 267: 25208-25212, 1992.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    GFPT1 (Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1))

    别名

    GFPT1

    背景

    Synonyms: Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA, IL3R

    Tissue Specificity: Brain.

    Background: Glucosamine-fructose-6-phosphate aminotransferase isomerizing 1 is an enzyme that in humans is encoded by the GFPT1 gene. This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate.

    分子量

    79 kDa

    基因ID

    2673

    UniProt

    Q06210

    途径

    ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process
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