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DNAJB6 抗体 (C-Term)

This anti-DNAJB6 antibody is a 兔 多克隆 antibody detecting DNAJB6 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602876
发货至: 中国

Quick Overview for DNAJB6 抗体 (C-Term) (ABIN7602876)

抗原

See all DNAJB6 抗体
DNAJB6 (DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6))

适用

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人, 小鼠, 大鼠

宿主

  • 39
  • 8

克隆类型

  • 42
  • 5
多克隆

标记

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This DNAJB6 antibody is un-conjugated

应用范围

  • 36
  • 21
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 7
    • 7
    • 6
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    C-Term

    原理

    Anti-DNAJB6 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-DNAJB6 Antibody Picoband® (ABIN7602876). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human DNAJB6.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human
    1. Bengoechea, R., Pittman, S. K., Tuck, E. P., True, H. L., Weihl, C. C. Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D. Hum. Molec. Genet. 24: 6588-6602, 2015. 2. Chuang, J.-Z., Zhou, H., Zhu, M., Li, S.-H., Li, X.-J., Sung, C.-H. Characterization of a brain-enriched chaperone, MRJ, that inhibits huntingtin aggregation and toxicity independently. J. Biol. Chem. 277: 19831-19838, 2002. 3. Couthouis, J., Raphael, A. R., Siskind, C., Findlay, A. R., Buenrostro, J. D., Greenleaf, W. J., Vogel, H., Day, J. W., Flanigan, K. M., Gitler, A. D. Exome sequencing identifies a DNAJB6 mutation in a family with dominantly-inherited limb-girdle muscular dystrophy. Neuromusc. Disord. 24: 431-435, 2014.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    DNAJB6 (DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6))

    别名

    DNAJB6

    背景

    Synonyms: DNAJB6, HSJ2, MRJ, MSJ1, DnaJ homolog subfamily B member 6, HHDJ1, Heat shock protein J2, HSJ-2, MRJ, MSJ-1

    Background: This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants, however, not all variants have been fully described.

    分子量

    27 kDa

    基因ID

    10049

    UniProt

    O75190
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