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Cathepsin S 抗体 (C-Term)

This anti-Cathepsin S antibody is a 兔多克隆 antibody detecting Cathepsin S in WB 和 FACS. Suitable for 人.

产品编号 ABIN7602873

发货至: 中国

Quick Overview for Cathepsin S 抗体 (C-Term) (ABIN7602873)

抗原

See all Cathepsin S (CTSS) 抗体

Cathepsin S (CTSS)

适用

55
18
9
5
3
2
2
2
2
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

50
9
8
3
1
1
1
1
1
1
1
1
1

This Cathepsin S antibody is un-conjugated

应用范围

51
39
23
22
18
9
7
4
4
3
2
1
1
1
1
1

Western Blotting (WB), Flow Cytometry (FACS)

Discover our top product CTSS Primary Antibody

抗原表位
14

9

5

4

3

3

3

1

1

1

1

1

1
C-Term

原理

Anti-CTSS Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-CTSS Antibody Picoband® (ABIN7602873). Tested in WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human CTSS.

亚型

IgG
anti-Cathepsin S (CTSS) (AA 115-331) antibody
CTSS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin S (CTSS) (AA 115-331) antibody
CTSS 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin S (CTSS) (AA 123-339) antibody
CTSS 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin S (CTSS) antibody
CTSS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin S (CTSS) (AA 115-331) antibody
CTSS 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin S (CTSS) antibody
CTSS 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 9B10 unconjugated Recombinant Antibody

anti-Cathepsin S (CTSS) (AA 1-331) antibody
CTSS 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin S (CTSS) (AA 210-240) antibody
CTSS 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19262 unconjugated

anti-Cathepsin S (CTSS) antibody
CTSS 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin S (CTSS) (AA 113-330) antibody
CTSS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Deussing, J., Roth, W., Rommerskirch, W., Wiederanders, B., von Figura, K., Peters, C. The genes of the lysosomal cysteine proteinases cathepsin B, H, L, and S map to different mouse chromosomes. Mammalian Genome 8: 241-245, 1997. 2. Driessen, C., Bryant, R. A., Lennon-Dumenil, A. M., Villadangos, J. A., Bryant, P. W., Shi, G. P., Chapman, H. A., Ploegh, H. L. Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells. J. Cell Biol. 147: 775-790, 1999. 3. Gelb, B. D., Shi, G.-P., Heller, M., Weremowicz, S., Morton, C., Desnick, R. J., Chapman, H. A. Structure and chromosomal assignment of the human cathepsin K gene. Genomics 41: 258-262, 1997.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

Cathepsin S (CTSS)

别名

CTSS

背景

Synonyms: CTSS, Cathepsin S, EC 3.4.22.27
Background: The preproprotein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that participates in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The mature protein cleaves the invariant chain of MHC class II molecules in endolysosomal compartments and enables the formation of antigen-MHC class II complexes and the proper display of extracellular antigenic peptides by MHC-II. The mature protein also functions as an elastase over a broad pH range. When secreted from cells, this protein can remodel components of the extracellular matrix such as elastin, collagen, and fibronectin. This gene is implicated in the pathology of many inflammatory and autoimmune diseases and, given its elastase activity, plays a significant role in some pulmonary diseases. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

分子量

25 kDa

基因ID

1520

UniProt

P25774

途径

Activation of Innate immune Response, Toll-Like Receptors Cascades

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