CRH 抗体 (C-Term)
Quick Overview for CRH 抗体 (C-Term) (ABIN7602869)
抗原
See all CRH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-CRF/CRH Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CRF-CRH Antibody Picoband® (ABIN7602869). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CRF/CRH, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Corticotropin Releasing Hormone (CRH) (AA 40-195) antibody
CRH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin Releasing Hormone (CRH) (AA 154-196) antibodyCRH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Corticotropin Releasing Hormone (CRH) (N-Term) antibodyCRH 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin Releasing Hormone (CRH) (AA 39-187) antibodyCRH 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin Releasing Hormone (CRH) antibodyMicroarray verified CRH 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB701026 unconjugated
anti-Corticotropin Releasing Hormone (CRH) antibodyMicroarray verified CRH 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB189288 unconjugated
anti-Corticotropin Releasing Hormone (CRH) (AA 185-196) antibodyCRH 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin Releasing Hormone (CRH) antibodyMicroarray verified CRH 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB561789 unconjugated
anti-Corticotropin Releasing Hormone (CRH) (AA 25-194) antibodyCRH 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin Releasing Hormone (CRH) (AA 29-45) antibodyCRH 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Arbiser, J. L., Morton, C. C., Bruns, G. A. P., Majzoub, J. A. Human corticotropin releasing hormone gene is located on the long arm of chromosome 8. Cytogenet. Cell Genet. 47: 113-116, 1988. 2. Asakura, H., Zwain, I. H., Yen, S. S. C. Expression of genes encoding corticotropin-releasing factor (CRF), type 1 CRF receptor, and CRF-binding protein and localization of the gene products in the human ovary. J. Clin. Endocr. Metab. 82: 2720-2725, 1997. 3. Behan, D. P., Heinrichs, S. C., Troncoso, J. C., Liu, X.-J., Kawas, C. H., Ling, N., De Souza, E. B. Displacement of corticotropin releasing factor from its binding protein as a possible treatment for Alzheimer's disease. Nature 378: 284-287, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CRH (Corticotropin Releasing Hormone (CRH))
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别名
- CRH
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背景
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Synonyms: CRH, Corticoliberin, Corticotropin-releasing factor, CRF, Corticotropin-releasing hormone
Background: This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer's disease. Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.
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分子量
- 25 kDa
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基因ID
- 1392
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UniProt
- P06850
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
抗原
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