Claudin 11 抗体 (C-Term)
Quick Overview for Claudin 11 抗体 (C-Term) (ABIN7602868)
抗原
See all Claudin 11 (CLDN11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-CLDN11 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CLDN11 Antibody Picoband® (ABIN7602868). Tested in WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CLDN11, which shares 85% amino acid (aa) sequence identity with both mouse and rat CLDN11.
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亚型
- IgG
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anti-Claudin 11 (CLDN11) (C-Term) antibody
CLDN11 适用: 人, 小鼠, 大鼠, Cow WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 11 (CLDN11) (AA 188-207) antibodyCLDN11 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 11 (CLDN11) (AA 101-218) antibodyCLDN11 适用: 小鼠, 大鼠, Cow, 绵羊 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 11 (CLDN11) antibodyCLDN11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 11 (CLDN11) (C-Term) antibodyCLDN11 适用: 人, 大鼠, Cow, 犬, 兔, 豚鼠, 马, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 11 (CLDN11) (AA 26-207) antibodyCLDN11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Claudin 11 (CLDN11) antibodyCLDN11 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 11 (CLDN11) (AA 23-82) antibodyCLDN11 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 11 (CLDN11) (AA 1-100) antibodyCLDN11 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 11 (CLDN11) (C-Term) antibodyCLDN11 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Bronstein, J. M., Kozak, C. A., Chen, X.-N., Wu, S., Danciger, M., Korenberg, J. R., Farber, D. B. Chromosomal localization of murine and human oligodendrocyte-specific protein genes. Genomics 34: 255-257, 1996. 2. Gow, A., Southwood, C. M., Li, J. S., Pariali, M., Riordan, G. P., Brodie, S. E., Danias, J., Bronstein, J. M., Kachar, B., Lazzarini, R. A. CNS myelin and Sertoli cell tight junction strands are absent in Osp/claudin-11 null mice. Cell 99: 649-659, 1999. 3. Maheras, K. J., Peppi, M., Ghoddoussi, F., Galloway, M. P., Perrine, S. A., Gow, A. Absence of Claudin 11 in CNS myelin perturbs behavior and neurotransmitter levels in mice. Sci. Rep. 8: 3798, 2018. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Claudin 11 (CLDN11)
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别名
- CLDN11
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背景
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Synonyms: CLDN11, OSP, OTM, Claudin-11, Oligodendrocyte-specific protein
Background: Claudin-11 is a protein that in humans is encoded by the CLDN11 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.
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分子量
- 22 kDa
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基因ID
- 5010
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UniProt
- O75508
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途径
- Hepatitis C
抗原
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