CENPB 抗体 (C-Term)
-
- 抗原 See all CENPB 抗体
- CENPB (Centromere Protein B (CENPB))
-
抗原表位
- C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CENPB antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- Anti-CENPB Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-CENPB Antibody Picoband® (ABIN7602867). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CENPB, identical to the related mouse sequence.
- 亚型
- IgG
- Top Product
- Discover our top product CENPB Primary Antibody
-
anti-Centromere Protein B (CENPB) (AA 1-599) antibody
CENPB 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (AA 1-599) antibodyCENPB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (AA 1-165) antibodyCENPB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) antibody (PE)CENPB 适用: 人 IF, ICC, IHC, FACS 宿主: 兔 Polyclonal PE
anti-Centromere Protein B (CENPB) (C-Term) antibodyCENPB 适用: 人, 小鼠, 大鼠, 马, Pig, 绵羊, Cow, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Cam, H. P., Noma, K., Ebina, H., Levin, H. L., Grewal, S. I. S. Host genome surveillance for retrotransposons by transposon-derived proteins. Nature 451: 431-436, 2008. 2. Earnshaw, W. C., Sullivan, K. F., Machlin, P. S., Cooke, C. A., Kaiser, D. A., Pollard, T. D., Rothfield, N. F., Cleveland, D. W. Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen. J. Cell Biol. 104: 817-829, 1987. 3. Fowler, K. J., Hudson, D. F., Salamonsen, L. A., Edmondson, S. R., Earle, E., Sibson, M. C., Choo, K. H. A. Uterine dysfunction and genetic modifiers in centromere protein B-deficient mice. Genome Res. 10: 30-41, 2000. - 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
- 抗原
- CENPB (Centromere Protein B (CENPB))
- 别名
- CENPB (CENPB 产品)
- 背景
-
Synonyms: Sodium- and chloride-dependent GABA transporter 1,GAT-1,Solute carrier family 6 member 1,SLC6A1,GABATR, GABT1, GAT1,
Tissue Specificity: Expressed in many tissues, highest levels in skeletal muscle.
Background: Centromere protein B also known as major centromere autoantigen B is an autoantigen protein of the cell nucleus. In humans, centromere protein B is encoded by the CENPB gene. This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.
- 分子量
- 80 kDa
- 基因ID
- 1059
- UniProt
- P07199
-
