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CD38 抗体 (C-Term)

This anti-CD38 antibody is a 兔 多克隆 antibody detecting CD38 in IHC. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7602864
发货至: 中国

Quick Overview for CD38 抗体 (C-Term) (ABIN7602864)

抗原

See all CD38 抗体
CD38

适用

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小鼠, 大鼠

宿主

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  • 1
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克隆类型

  • 170
  • 83
  • 1
多克隆

标记

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This CD38 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    • 2
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    C-Term

    原理

    Anti-Cd38 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Cd38 Antibody Picoband® (ABIN7602864). Tested in IHC applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Cd38, which shares 81.8% and 86.7% amino acid (aa) sequence identity with human and rat Cd38, respectively.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
    1. Cockayne, D. A., Muchamuel, T., Grimaldi, J. C., Muller-Steffner, H., Randall, T. D., Lund, F. E., Murray, R., Schuber, F., Howard, M. C. Mice deficient for the ecto-nicotinamide adenine dinucleotide glycohydrolase CD38 exhibit altered humoral immune responses. Blood 92: 1324-1333, 1998. 2. Ferrero, E., Malavasi, F. Human CD38, a leukocyte receptor and ectoenzyme, is a member of a novel eukaryotic gene family of nicotinamide adenine dinucleotide +/-converting enzymes: extensive structure homology with the genes for murine bone marrow stromal cell antigen 1 and aplysian ADP-ribosyl cyclase. J. Immun. 159: 3858-3865, 1997. 3. Ferrero, E., Saccucci, F., Malavasi, F. The human CD38 gene: polymorphism, CpG island, and linkage to the CD157 (BST-1) gene. Immunogenetics 49: 597-604, 1999.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CD38

    背景

    Synonyms: Receptor-type tyrosine-protein kinase FLT3, 2.7.10.1, FL cytokine receptor, Fetal liver kinase 2, FLK-2, Fms-like tyrosine kinase 3, FLT-3, Tyrosine-protein kinase receptor flk-2, CD135, Flt3, Flk-2, Flt-3,

    Tissue Specificity: Hematopoietic stem and progenitor cell- enriched populations. Found in brain, placenta and testis.

    Background: The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.

    分子量

    45 kDa

    基因ID

    12494

    UniProt

    P56528
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