TNNI3 抗体 (C-Term)
Quick Overview for TNNI3 抗体 (C-Term) (ABIN7602860)
抗原
See all TNNI3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Cardiac Troponin I/TNNI3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Cardiac Troponin I/TNNI3 Antibody Picoband® (ABIN7602860). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Cardiac Troponin I/TNNI3, which shares 95.5% amino acid (aa) sequence identity with mouse and rat TNNI3.
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亚型
- IgG
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anti-Cardiac Troponin I (TNNI3) (AA 102-210) antibody
TNNI3 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 1-211) antibodyTNNI3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 2-211) antibodyTNNI3 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) antibodyTNNI3 适用: 人, 犬, 猴 WB, IF 宿主: 小鼠 Monoclonal 4E5 unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 1-211) antibodyTNNI3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 117-127) antibodyVerified TNNI3 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 2-210) antibodyTNNI3 适用: 人 ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (pSer44) antibodyTNNI3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 1-203) antibodyTNNI3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 1-203) antibodyTNNI3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D2 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
1. Arad, M., Penas-Lado, M., Monserrat, L., Maron, B. J., Sherrid, M., Ho, C. Y., Barr, S., Karim, A., Olson, T. M., Kamisago, M., Seidman, J. G., Seidman, C. E. Gene mutations in apical hypertrophic cardiomyopathy. Circulation 112: 2805-2811, 2005. 2. Barton, P. J. R., Cullen, M. E., Townsend, P. J., Brand, N. J., Mullen, A. J., Norman, D. A. M., Bhavsar, P. K., Yacoub, M. H. Close physical linkage of human troponin genes: organization, sequence, and expression of the locus encoding cardiac troponin I and slow skeletal troponin T. Genomics 57: 102-109, 1999. 3. Bermingham, N., Hernandez, D., Balfour, A., Gilmour, F., Martin, J. E., Fisher, E. M. C. Mapping TNNC1, the gene that encodes cardiac troponin I in the human and mouse. Genomics 30: 620-622, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TNNI3 (Cardiac Troponin I (TNNI3))
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别名
- TNNI3
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背景
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Synonyms: Alkaline phosphatase, placental type,3.1.3.1,Alkaline phosphatase Regan isozyme,Placental alkaline phosphatase 1,PLAP-1,ALPP,PLAP,
Tissue Specificity: Detected in placenta (at protein level). .
Background: Troponin I, cardiac muscle is a protein that in humans is encoded by the TNNI3 gene. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19.
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分子量
- 24 kDa
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基因ID
- 7137
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UniProt
- P19429
抗原
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