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TNNI3 抗体 (C-Term)

This anti-TNNI3 antibody is a 兔 多克隆 antibody detecting TNNI3 in WB. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7602860
发货至: 中国
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Quick Overview for TNNI3 抗体 (C-Term) (ABIN7602860)

抗原

See all TNNI3 抗体
TNNI3 (Cardiac Troponin I (TNNI3))

适用

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  • 21
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小鼠, 大鼠

宿主

  • 110
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  • 10
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  • 3
  • 1
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克隆类型

  • 119
  • 110
  • 2
多克隆

标记

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  • 1
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  • 1
  • 1
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  • 1
This TNNI3 antibody is un-conjugated

应用范围

  • 183
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  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 9
    • 7
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    • 5
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    • 1
    • 1
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    C-Term

    原理

    Anti-Cardiac Troponin I/TNNI3 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Cardiac Troponin I/TNNI3 Antibody (ABIN7602860). Tested in WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Cardiac Troponin I/TNNI3, which shares 95.5% amino acid (aa) sequence identity with mouse and rat TNNI3.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    TNNI3 (Cardiac Troponin I (TNNI3))

    别名

    TNNI3

    背景

    Synonyms: Alkaline phosphatase, placental type,3.1.3.1,Alkaline phosphatase Regan isozyme,Placental alkaline phosphatase 1,PLAP-1,ALPP,PLAP,

    Tissue Specificity: Detected in placenta (at protein level). .

    Background: Troponin I, cardiac muscle is a protein that in humans is encoded by the TNNI3 gene. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19.

    分子量

    24 kDa

    基因ID

    7137

    UniProt

    P19429
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