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ARL3 抗体 (C-Term)

This anti-ARL3 antibody is a 兔 多克隆 antibody detecting ARL3 in WB, IF, FACS 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602850
发货至: 中国

Quick Overview for ARL3 抗体 (C-Term) (ABIN7602850)

抗原

See all ARL3 抗体
ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ARL3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    原理

    Anti-ARL3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-ARL3 Antibody Picoband® (ABIN7602850). Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human ARL3, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Alkanderi, S., Molinari, E., Shaheen, R., Elmaghloob, Y., Stephen, L. A., Sammut, V., Ramsbottom, S. A., Srivastava, S., Cairns, G., Edwards, N., Rice, S. J., Ewida, N., Alhashem, A., White, K., Miles, C. G., Steel, D. H., Alkuraya, F. S., Ismail, S., Sayer, J. A. ARL3 mutations cause Joubert syndrome by disrupting ciliary protein composition. Am. J. Hum. Genet. 103: 612-620, 2018. 2. Cavenagh, M. M., Breiner, M., Schurmann, A., Rosenwald, A. G., Terui, T., Zhang, C., Randazzo, P. A., Adams, M., Joost, H. G., Kahn, R. A. ADP-ribosylation factor (ARF)-like 3, a new member of the ARF family of GTP-binding proteins cloned from human and rat tissues. J. Biol. Chem. 269: 18937-18942, 1994. 3. Grayson, C., Bartolini, F., Chapple, J. P., Willison, K. R., Bhamidipati, A., Lewis, S. A., Luthert, P. J., Hardcastle, A. J., Cowan, N. J., Cheetham, M. E. Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3. Hum. Molec. Genet. 11: 3065-3074, 2002.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

    别名

    ARL3

    背景

    Synonyms: ARL3, ARFL3, ADP-ribosylation factor-like protein 3

    Background: ADP-ribosylation factor-like protein 3 is a protein that in humans is encoded by the ARL3 gene. Enables GDP binding activity, GTP binding activity, and microtubule binding activity. Involved in several processes, including cilium assembly, protein localization to cilium, and small GTPase mediated signal transduction. Acts upstream of or within post-Golgi vesicle-mediated transport. Located in several cellular components, including microtubule cytoskeleton, midbody, and photoreceptor connecting cilium. Implicated in Joubert syndrome and retinitis pigmentosa 83.

    分子量

    23 kDa

    基因ID

    403

    UniProt

    P36405
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