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ARL1 抗体 (C-Term)

This anti-ARL1 antibody is a 兔 多克隆 antibody detecting ARL1 in WB, IHC, IF 和 FACS. Suitable for 人.
产品编号 ABIN7602848
发货至: 中国

Quick Overview for ARL1 抗体 (C-Term) (ABIN7602848)

抗原

See all ARL1 抗体
ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ARL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
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    C-Term

    原理

    Anti-ARL1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ARL1 Antibody Picoband® (ABIN7602848). Tested in Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human ARL1, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human
    1. Gross, M. B. Personal Communication. Baltimore, Md. 7/25/2012. 2. Hong, J.-X., Lee, F.-J. S., Patton, W. A., Lin, C. Y., Moss, J., Vaughan, M. Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1). J. Biol. Chem. 273: 15872-15876, 1998. 3. Lu, L., Tai, G., Hong, W. Autoantigen golgin-97, an effector of Arl1 GTPase, participates in traffic from the endosome to the trans-Golgi network. Molec. Biol. Cell 15: 4426-4443, 2004.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

    别名

    ARL1

    背景

    Synonyms: ATP-dependent RNA helicase DDX1, DEAD box protein 1, DEAD box protein retinoblastoma, DBP-RB, DDX1

    Tissue Specificity: Highest levels of transcription in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin including the retina, brain, and spinal cord.

    Background: ADP-ribosylation factor-like protein 1 is a protein that in humans is encoded by the ARL1 gene. The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    20 kDa

    基因ID

    400

    UniProt

    P40616
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