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ACADSB 抗体 (C-Term)

ACADSB 适用: 人, 大鼠, 小鼠, 猴 WB, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7602837
发货至: 中国
  • 抗原 See all ACADSB 抗体
    ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))
    抗原表位
    • 6
    • 1
    • 1
    • 1
    C-Term
    适用
    • 12
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 猴
    宿主
    • 12
    克隆类型
    • 12
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    This ACADSB antibody is un-conjugated
    应用范围
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    原理
    Anti-SBCAD/ACADSB Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-SBCAD/ACADSB Antibody Picoband® (ABIN7602837). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human SBCAD/ACADSB, identical to the related mouse and rat sequences.
    亚型
    IgG
    Top Product
    Discover our top product ACADSB Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
    1. Alfardan, J., Mohsen, A.-W., Copeland, S., Ellison, J., Keppen-Davis, L., Rohrbach, M., Powell, B. R., Gillis, J., Matern, D., Kant, J., Vockley, J. Characterization of new ACADSB gene sequence mutations and clinical implications in patients with 2-methylbutyrylglycinuria identified by newborn screening. Molec. Genet. Metab. 100: 333-338, 2010. 2. Andresen, B. S., Christensen, E., Corydon, T. J., Bross, P., Pilgaard, B., Wanders, R. J. A., Ruiter, J. P. N., Simonsen, H., Winter, V., Knudsen, I., Schroeder, L. D., Gregersen, N., Skovby, F. Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism. Am. J. Hum. Genet. 67: 1095-1103, 2000. 3. Arden, K. C., Viars, C. S., Fu, K., Rozen, R. Localization of short/branched chain acyl-CoA dehydrogenase (ACADSB) to human chromosome 10. Genomics 25: 743-745, 1995.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))
    别名
    ACADSB (ACADSB 产品)
    背景

    Synonyms: Annexin A8 ,Annexin VIII ,Annexin-8 ,Vascular anticoagulant-beta ,VAC-beta ,ANXA8 ,ANX8,

    Tissue Specificity: Ubiquitously expressed.

    Background: ACADSB is a human gene that encodes short/branched chain specific acyl-CoA dehydrogenase (SBCAD), an enzyme in the acyl CoA dehydrogenase family.Short/branched chain acyl-CoA dehydrogenase (ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa.

    分子量
    40-44 kDa
    基因ID
    36
    UniProt
    P45954
    途径
    Monocarboxylic Acid Catabolic Process
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