RAG1 抗体 (C-Term)
Quick Overview for RAG1 抗体 (C-Term) (ABIN7602835)
抗原
See all RAG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-RAG1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RAG1 Antibody Picoband® (ABIN7602835). Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human RAG1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Recombination Activating Gene 1 (RAG1) (AA 818-868) antibody
RAG1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Recombination Activating Gene 1 (RAG1) (AA 818-868) antibodyRAG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Recombination Activating Gene 1 (RAG1) antibodyRAG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Recombination Activating Gene 1 (RAG1) (AA 946-995) antibodyRAG1 适用: 小鼠, 人, Pig, 大鼠, 小鸡, 兔, 非洲爪蟾, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Recombination Activating Gene 1 (RAG1) (AA 1-270) antibodyRAG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Recombination Activating Gene 1 (RAG1) (C-Term) antibodyRAG1 适用: 小鼠, 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
1. Agrawal, A., Eastman, Q. M., Schatz, D. G. Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature 394: 744-751, 1998. 2. Blanquet, V., Turleau, C., Goossens, M., Besmond, C. Assignment of the human recombination activating gene 1 (RAG1) to the 14q21.3-q22.2 region. Genomics 13: 488-489, 1992. 3. Corneo, B., Moshous, D., Gungor, T., Wulffraat, N., Philippet, P., Le Deist, F., Fischer, A., de Villartay, J.-P. Identical mutations in RAG1 or RAG2 genes leading to defective V(D)J recombinase activity can cause either T-B-severe combined immune deficiency or Omenn syndrome. Blood 97: 2772-2776, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RAG1 (Recombination Activating Gene 1 (RAG1))
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别名
- RAG1
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背景
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Synonyms: Interferon alpha/beta receptor 1,IFN-R-1,IFN-alpha/beta receptor 1,Cytokine receptor class-II member 1,Cytokine receptor family 2 member 1,CRF2-1,Type I interferon receptor 1,IFNAR1,IFNAR,
Tissue Specificity: IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. .
Background: Recombination activating gene 1 also known as RAG-1 is a protein that in humans is encoded by the RAG1 gene. The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
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分子量
- 120 kDa
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基因ID
- 5896
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UniProt
- P15918
抗原
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