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LSM2 抗体 (C-Term)

This anti-LSM2 antibody is a 兔 多克隆 antibody detecting LSM2 in WB, IHC, FACS, ICC 和 IF. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7602832
发货至: 中国

Quick Overview for LSM2 抗体 (C-Term) (ABIN7602832)

抗原

See all LSM2 抗体
LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 11
  • 4
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克隆类型

  • 14
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多克隆

标记

  • 17
This LSM2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    原理

    Anti-LSM2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-LSM2 Antibody Picoband® (ABIN7602832). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human LSM2, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
    Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Achsel, T., Brahms, H., Kastner, B., Bachi, A., Wilm, M., Luhrmann, R. A doughnut-shaped heteromer of human Sm-like proteins binds to the 3-prime end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. EMBO J. 18: 5789-5802, 1999. 2. Ingelfinger, D., Arndt-Jovin, D. J., Luhrmann, R., Achsel, T. The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrn1 in distinct cytoplasmic foci. RNA 8: 1489-1501, 2002. 3. Salgado-Garrido, J., Bragado-Nilsson, E., Kandels-Lewis, S., Seraphin, B. Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J. 18: 3451-3462, 1999.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))

    别名

    LSM2

    背景

    Synonyms: C-C motif chemokine 16, Chemokine CC-4, HCC-4, Chemokine LEC, IL-10-inducible chemokine, LCC-1, Liver-expressed chemokine, Lymphocyte and monocyte chemoattractant, LMC, Monotactin-1, MTN-1, NCC-4, Small-inducible cytokine A16, CCL16, ILINCK, NCC4, SCYA16

    Tissue Specificity: Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma- activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.

    Background: U6 snRNA-associated Sm-like protein LSm2 is a protein that in humans is encoded by the LSM2 gene. This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo (U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19.

    分子量

    11 kDa

    基因ID

    57819

    UniProt

    Q9Y333

    途径

    Ribonucleoprotein Complex Subunit Organization
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