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Arylsulfatase B 抗体 (C-Term)

This anti-Arylsulfatase B antibody is a 兔 多克隆 antibody detecting Arylsulfatase B in WB. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7602811
发货至: 中国

Quick Overview for Arylsulfatase B 抗体 (C-Term) (ABIN7602811)

抗原

See all Arylsulfatase B (ARSB) 抗体
Arylsulfatase B (ARSB)

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Arylsulfatase B antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    Anti-Arsb Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Arsb Antibody Picoband® (ABIN7602811). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Arsb, which shares 88.2% and 94.1% amino acid (aa) sequence identity with human and rat Arsb, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    1. Crawley, A. C., Brooks, D. A., Muller, V. J., Petersen, B. A., Isaac, E. L., Bielicki, J., King, B. M., Boulter, C. D., Moore, A. J., Fazzalari, N. L., Anson, D. S., Byers, S., Hopwood, J. J. Enzyme replacement therapy in a feline model of Maroteaux-Lamy syndrome. J. Clin. Invest. 97: 1864-1873, 1996. 2. Crawley, A. C., Niedzielski, K. H., Isaac, E. L., Davey, R. C. A., Byers, S., Hopwood, J. J. Enzyme replacement therapy from birth in a feline model of mucopolysaccharidosis type VI. J. Clin. Invest. 99: 651-662, 1997. 3. Crawley, A. C., Yogalingam, G., Muller, V. J., Hopwood, J. J. Two mutations within a feline mucopolysaccharidosis type VI colony cause three different clinical phenotypes. J. Clin. Invest. 101: 109-119, 1998.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Arylsulfatase B (ARSB)

    别名

    Arsb

    背景

    Synonyms: Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27

    Tissue Specificity: Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta. Detected in melanocytes, and in most tumor cell lines examined. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells.

    Background: Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targeted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

    分子量

    66-70 kDa

    基因ID

    11881

    UniProt

    P50429

    途径

    Glycosaminoglycan Metabolic Process
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