Claudin 7 抗体 (C-Term)
Quick Overview for Claudin 7 抗体 (C-Term) (ABIN7602803)
抗原
See all Claudin 7 (CLDN7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Claudin 7/CLDN-7 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Claudin 7/CLDN-7 Antibody Picoband® (ABIN7602803). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse Claudin 7/CLDN-7, which shares 87% and 100% amino acid (aa) sequence identity with human and rat Claudin 7/CLDN-7, respectively.
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亚型
- IgG
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anti-Claudin 7 (CLDN7) (Tyr210) antibody
CLDN7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 7 (CLDN7) antibodyCLDN7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 7 (CLDN7) (C-Term) antibodyCLDN7 适用: 人 WB, ELISA, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal unconjugated
anti-Claudin 7 (CLDN7) (C-Term) antibodyCLDN7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 7 (CLDN7) (AA 29-211) antibodyCLDN7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Claudin 7 (CLDN7) (C-Term) antibodyCLDN7 适用: 人, 小鼠, 犬 WB, IHC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 7 (CLDN7) (AA 172-201), (C-Term) antibodyCLDN7 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23672 unconjugated
anti-Claudin 7 (CLDN7) (AA 179-209), (C-Term) antibodyCLDN7 适用: 人 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Claudin 7 (CLDN7) (AA 21-100) antibodyCLDN7 适用: 人 ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 7 (CLDN7) antibodyCLDN7 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse
1. Coyne, C. B., Gambling, T. M., Boucher, R. C., Carson, J. L., Johnson, L. G. Role of claudin interactions in airway tight junctional permeability. Am. J. Physiol. Lung Cell. Molec. Physiol. 285: L1166-L1178, 2003. 2. Kominsky, S. L., Argani, P., Korz, D., Evron, E., Raman, V., Garrett, E., Rein, A., Sauter, G., Kallioniemi, O.-P., Sukumar, S. Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast. Oncogene 22: 2021-2033, 2003. 3. Morita, K., Furuse, M., Fujimoto, K., Tsukita, S. Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc. Nat. Acad. Sci. 96: 511-516, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Claudin 7 (CLDN7)
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别名
- Cldn7
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背景
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Synonyms: AF4/FMR2 family member 4,ALL1-fused gene from chromosome 5q31 protein,Protein AF-5q31,Major CDK9 elongation factor-associated protein,AFF4,AF5Q31, MCEF,HSPC092,
Tissue Specificity: Ubiquitously expressed. Strongly expressed in heart, placenta, skeletal muscle, pancreas and to a lower extent in brain. .
Background: Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 22 kDa
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基因ID
- 53624
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UniProt
- Q9Z261
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途径
- Hepatitis C
抗原
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