TJP2 抗体 (C-Term)
Quick Overview for TJP2 抗体 (C-Term) (ABIN7602800)
抗原
See all TJP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-TJP2/ZO2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TJP2/ZO2 Antibody Picoband® (ABIN7602800). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at C-terminus of human TJP2/ZO2, identical to the related mouse sequence.
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亚型
- IgG
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anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 307-669) antibody
TJP2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 951-1190) antibodyTJP2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 1165-1183) antibodyTJP2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 121-218) antibodyTJP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (C-Term) antibodyTJP2 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 1-1190) antibodyTJP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (C-Term) antibodyTJP2 适用: 人, 大鼠, 犬, Cow, 豚鼠, 兔, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 468-517) antibodyTJP2 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) antibodyTJP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) antibodyTJP2 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Duclos, F., Rodius, F., Wrogemann, K., Mandel, J.-L., Koenig, M. The Friedreich ataxia region: characterization of two novel genes and reduction of the critical region to 300 kb. Hum. Molec. Genet. 3: 909-914, 1994. 2. Itoh, M., Furuse, M., Morita, K., Kubota, K., Saitou, M., Tsukita, S. binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J. Cell Biol. 147: 1351-1363, 1999. 3. Walsh, T., Pierce, S. B., Lenz, D. R., Brownstein, Z., Dagan-Rosenfeld, O., Shahin, H., Roeb, W., McCarthy, S., Nord, A. S., Gordon, C. R., Ben-Neriah, Z., Sebat, J., Kanaan, M., Lee, M. K., Frydman, M., King, M.-C., Avraham, K. B. Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51. Am. J. Hum. Genet. 87: 101-109, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))
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别名
- TJP2
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背景
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Synonyms: CD3 antigen, epsilon polypeptide, CD3e molecule, Cd3e, Cd3e_predicted, rCG_58471
Background: TJP2 (Tight Junction Protein 2), also known as Zona Occludens 2 or ZO2 is a protein that in humans is encoded by the TJP2 gene. Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. Duclos et al. (1994) mapped the TJP2 gene telomeric to the Friedreich ataxia critical region on chromosome 9q13-q21. TJP2 lies about 70 kb centromeric to the X123 gene and is transcribed in the centromere-to-telomere ion. Using in vitro assays and immunoprecipitation studies, Itoh et al. (1999) showed that the mouse Tjp1, Tjp2, and Tjp3 PDZ1 domains interacted with the C-terminal cytoplasmic domains of Cldn1 through Cldn8. In the mouse inner ear, Walsh et al. (2010) found that Tjp2 expression decreased rapidly between E16.5 and age 1 week to a level in adult mice that was approximately 50 % of the level at birth (P0).
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分子量
- 150 kDa
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基因ID
- 9414
抗原
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