ELP3/KAT9 抗体 (C-Term)
Quick Overview for ELP3/KAT9 抗体 (C-Term) (ABIN7602789)
抗原
See all ELP3/KAT9 (ELP3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Anti-KAT9/ELP3 Antibody Picoband® (monoclonal, 8B4)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-KAT9/ELP3 Antibody Picoband® (monoclonal, 8B4) (ABIN7602789). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human KAT9/ELP3, identical to the related mouse sequence.
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亚型
- IgG2a
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anti-Elongator complex protein 3 (ELP3) (AA 1-85) antibody
ELP3 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Elongator complex protein 3 (ELP3) antibodyELP3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Elongator complex protein 3 (ELP3) (AA 1-547) antibodyELP3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Elongator complex protein 3 (ELP3) (AA 358-547) antibodyELP3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Elongator complex protein 3 (ELP3) antibodyELP3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Elongator complex protein 3 (ELP3) (AA 1-547) antibodyELP3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Elongator complex protein 3 (ELP3) (Center) antibodyELP3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elongator complex protein 3 (ELP3) (AA 9-44), (N-Term) antibodyELP3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB14284 unconjugated
anti-Elongator complex protein 3 (ELP3) antibodyELP3 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Elongator complex protein 3 (ELP3) (Internal Region) antibodyELP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
1. Hawkes NA, Otero G, Winkler GS, Marshall N, Dahmus ME, Krappmann D, Scheidereit C, Thomas CL, Schiavo G, Erdjument-Bromage H, Tempst P, Svejstrup JQ (Jan 2002). "Purification and characterization of the human elongator complex". J Biol Chem. 277 (4): 3047-52. 2. Creppe C, Malinouskaya L, Volvert ML, Gillard M, Close P, Malaise O, Laguesse S, Cornez I, Rahmouni S, Ormenese S, Belachew S, Malgrange B, Chapelle JP, Siebenlist U, Moonen G, Chariot A, Nguyen L (Feb 2009). "Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin". Cell. 136 (3): 551-64. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))
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别名
- ELP3
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背景
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Synonyms: Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB, CST6, STFB
Tissue Specificity: Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.
Background: Elongator complex protein 3, also named KAT9, is aproteinthat in humans is encoded by theELP3gene. It is mapped to 8p21.1. ELP3 is the catalytichistone acetyltransferasesubunit of theRNA polymeraseII elongator complex, which is a component of the RNA polymerase II (Pol II)holoenzymeand is involved in transcriptional elongation. ELP3 supports the migration and branching ofprojection neuronsthroughacetylationof alpha-tubulin in the developingcerebral cortex. In mammals, ELP3 is important for paternalDNA demethylationafterfertilization.ELP3 is potentially involved in cellular redoxhomeostasisby mediating the acetylation ofglucose-6-phosphate dehydrogenase. Besides, ELP3 may play a role inchromatin remodelingand is involved in acetylation ofhistones H3and probablyH4.
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分子量
- 62 kDa
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基因ID
- 55140
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UniProt
- Q9H9T3
抗原
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