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IFI30 抗体 (C-Term)

This anti-IFI30 antibody is a 兔 多克隆 antibody detecting IFI30 in WB, IHC, FACS 和 IF. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7602781
发货至: 中国

Quick Overview for IFI30 抗体 (C-Term) (ABIN7602781)

抗原

See all IFI30 抗体
IFI30 (Interferon, gamma-Inducible Protein 30 (IFI30))

适用

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小鼠, 大鼠

宿主

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克隆类型

  • 30
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多克隆

标记

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This IFI30 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
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    C-Term

    原理

    Anti-GILT/IFI30 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-GILT/IFI30 Antibody Picoband® (ABIN7602781). Tested in Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse GILT/IFI30, which shares 84.2% and 89.5% amino acid (aa) sequence identity with human and rat GILT/IFI30, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse
    Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Mouse, Rat
    Immunofluorescence, 5 μg/mL, Mouse, Rat
    Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Mouse
    1. Arunachalam, B., Phan, U. T., Geuze, H. J., Cresswell, P. Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT). Proc. Nat. Acad. Sci. 97: 745-750, 2000. 2. Maric, M., Arunachalam, B., Phan, U. T., Dong, C., Garrett, W. S., Cannon, K. S., Alfonso, C., Karlsson, L., Flavell, R. A., Cressell, P. Defective antigen processing in GILT-free mice. Science 294: 1361-1365, 2001. 3. Phan, U. T., Arunachalam, B., Cresswell, P. Gamma-interferon-inducible lysosomal thiol reductase (GILT): maturation, activity, and mechanism of action. J. Biol. Chem. 275: 25907-25914, 2000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    IFI30 (Interferon, gamma-Inducible Protein 30 (IFI30))

    别名

    Ifi30

    背景

    Synonyms: Protein phosphatase 1 regulatory subunit 14A,17 kDa PKC-potentiated inhibitory protein of PP1,Protein kinase C-potentiated inhibitor protein of 17 kDa,CPI-17,PPP1R14A,CPI17, PPP1INL,

    Tissue Specificity: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. .

    Background: Gamma-interferon-inducible lysosomal thiol reductase is an enzyme that, in humans, is encoded by the IFI30 gene. The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.

    分子量

    28 kDa

    基因ID

    65972
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