Radixin 抗体 (C-Term)
Quick Overview for Radixin 抗体 (C-Term) (ABIN7602767)
抗原
See all Radixin (RDX) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Radixin/RDX Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Radixin/RDX Antibody Picoband® (ABIN7602767). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Radixin/RDX, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Radixin (RDX) antibody
KO Validated RDX 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Radixin (RDX) (Internal Region) antibodyVerified RDX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Radixin (RDX) (AA 1-583) antibodyRDX 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Radixin (RDX) (AA 5-295) antibodyRDX 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Radixin (RDX) antibodyRDX 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Radixin (RDX) (AA 1-583) antibodyRDX 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Radixin (RDX) (AA 1-583) antibodyRDX 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Radixin (RDX) (AA 1-583) antibodyRDX 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Radixin (RDX) (AA 466-495) antibodyRDX 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Radixin (RDX) (AA 1-583) antibodyRDX 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E12 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Vaiskunaite R, Adarichev V, Furthmayr H, Kozasa T, Gudkov A, Voyno-Yasenetskaya TA (August 2000). "Conformational activation of radixin by G13 protein alpha subunit". J. Biol. Chem. 275 (34): 26206-12. 2. Wilgenbus KK, Milatovich A, Francke U, Furthmayr H (June 1993). "Molecular cloning, cDNA sequence, and chromosomal assignment of the human radixin gene and two dispersed pseudogenes". Genomics. 16 (1): 199-206. 3. Khan SY, Ahmed ZM, Shabbir MI, Kitajiri S, Kalsoom S, Tasneem S, Shayiq S, Ramesh A, Srisailpathy S, Khan SN, Smith RJ, Riazuddin S, Friedman TB, Riazuddin S (April 2007). "Mutations of the RDX gene cause nonsyndromic hearing loss at the DFNB24 locus". Hum Mutat. 28 (5): 417-23. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Radixin (RDX)
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别名
- RDX
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背景
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Synonyms: Radixin, RDX
Tissue Specificity: Ubiquitous. Expressed in the rod and cone photoreceptors, extending from the tips of the outer segment (OS) through the inner segment (IS) and outer nuclear layer (ONL) and into the synaptic terminals of the outer plexiform layer (ONL). Also detected in the bipolar, horizontal and amacrine cells in the inner nuclear layer (INL), extending to the inner plexiform layer (IPL) and though the ganglion cell layer (GCL) and into the nerve fiber layer (NFL) (at protein level).
Background: Radixin is a protein that in humans is encoded by the RDX gene. Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 88 kDa
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基因ID
- 5962
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UniProt
- P35241
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途径
- Regulation of Actin Filament Polymerization, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
抗原
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