Acetyl-CoA Carboxylase beta 抗体 (C-Term)
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Quick Overview for Acetyl-CoA Carboxylase beta 抗体 (C-Term) (ABIN7602757)
抗原
See all Acetyl-CoA Carboxylase beta (ACACB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Acetyl Coenzyme A Carboxylase/ACACB Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Acetyl Coenzyme A Carboxylase/ACACB Antibody (ABIN7602757). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Acetyl Coenzyme A Carboxylase/ACACB, which shares 64.7% amino acid (aa) sequence identity with mouse Acetyl Coenzyme A Carboxylase/ACACB.
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亚型
- IgG
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anti-Acetyl-CoA Carboxylase beta (ACACB) (AA 29-249) antibody
ACACB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase beta (ACACB) antibodyACACB 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB3230 unconjugated Recombinant Antibody
anti-Acetyl-CoA Carboxylase beta (ACACB) (Internal Region) antibodyRecent ACACB 适用: 人 ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase beta (ACACB) (Internal Region) antibodyVerified ACACB 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase beta (ACACB) (N-Term) antibodyACACB 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase beta (ACACB) (AA 22-120) antibodyACACB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C11 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Acetyl-CoA Carboxylase beta (ACACB)
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别名
- ACACB
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背景
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Synonyms: Acetyl-CoA carboxylase 2, ACC-beta, Biotin carboxylase, ACACB, ACC2, ACCB
Tissue Specificity: Widely expressed with highest levels in heart, skeletal muscle, liver, adipose tissue, mammary gland, adrenal gland and colon (PubMed:9099716). Isoform 3 is expressed in skeletal muscle, adipose tissue and liver (at protein level) (PubMed:19190759). Isoform 3 is detected at high levels in adipose tissue with lower levels in heart, liver, skeletal muscle and testis (PubMed:19190759).
Background: Acetyl-CoA carboxylase 2 also known as ACC-beta or ACC2 is an enzyme that in humans is encoded by the ACACB gene. It is mapped to 12q24.11. Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.
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分子量
- 277 kDa
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基因ID
- 32
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UniProt
- O00763
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途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process
抗原
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