CDKN1C 抗体 (C-Term)
Quick Overview for CDKN1C 抗体 (C-Term) (ABIN7602751)
抗原
See all CDKN1C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-p57 Kip2/CDKN1C Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-p57 Kip2/CDKN1C Antibody Picoband® (ABIN7602751). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human p57 Kip2/CDKN1C, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) antibody
CDKN1C 适用: 人 WB, ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 1F4A9 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) antibodyCDKN1C 适用: 人 WB, ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 8G5D5 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) antibodyCDKN1C 适用: 人 IHC (f) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (AA 291-343) antibodyCDKN1C 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (N-Term) antibodyCDKN1C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) antibodyCDKN1C 适用: 人 IF, FACS, IHC (f) 宿主: 小鼠 Monoclonal SPM308 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) antibodyCDKN1C 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal KP10 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (pThr310) antibodyCDKN1C 适用: 人 WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (AA 1-100) antibodyCDKN1C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (AA 267-316), (pThr310) antibodyCDKN1C 适用: 人, 小鼠 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
1. Algar, E., Brickell, S., Deeble, G., Amor, D., Smith, P. Analysis of CDKN1C in Beckwith Wiedemann syndrome. Hum. Mutat. 15: 497-508, 2000. 2. Algar, E. M., Deeble, G. J., Smith, P. J. CDKN1C expression in Beckwith-Wiedemann syndrome patients with allele imbalance. J. Med. Genet. 36: 524-531, 1999. 3. Arboleda, V. A., Lee, H., Parnaik, R., Fleming, A., Banerjee, A., Ferraz-de-Souza, B., Delot, E. C., Rodriguez-Fernandez, I. A., Braslavsky, D., Bergada, I., Dell'Angelica, E. C., Nelson, S. F., Martinez-Agosto, J. A., Achermann, J. C., Vilain, E. Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome. Nature Genet. 44: 788-792, 2012. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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别名
- CDKN1C
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背景
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Synonyms: Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2, CDKN1C, KIP2
Tissue Specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver.
Background: Cyclin-dependent kinase inhibitor 1C (p57, Kip2), also known as CDKN1C, is a protein which in humans is encoded by the CDKN1C imprinted gene. It is mapped to 11p15.4. This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
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分子量
- 57 kDa
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基因ID
- 1028
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UniProt
- P49918
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途径
- Cell Division Cycle, Dopaminergic Neurogenesis
抗原
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