CHRM1 抗体 (C-Term)
Quick Overview for CHRM1 抗体 (C-Term) (ABIN7602749)
抗原
See all CHRM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Muscarinic Acetylcholine Receptor 1/CHRM1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Muscarinic Acetylcholine Receptor 1/CHRM1 Antibody (ABIN7602749). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Muscarinic Acetylcholine Receptor 1/CHRM1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 210-363) antibody
CHRM1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Muscarinic Acetylcholine Receptor M1 (CHRM1) (C-Term) antibodyCHRM1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 321-420) antibodyCHRM1 适用: 大鼠, 人, 小鼠, 山羊 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Muscarinic Acetylcholine Receptor M1 (CHRM1) (C-Term) antibodyCHRM1 适用: 大鼠, 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Muscarinic Acetylcholine Receptor M1 (CHRM1) (C-Term) antibodyVerified CHRM1 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Muscarinic Acetylcholine Receptor M1 (CHRM1) (C-Term) antibodyCHRM1 适用: 大鼠, 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 227-353) antibodyKO Validated CHRM1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 210-366) antibodyCHRM1 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 331-367), (C-Term) antibodyCHRM1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51455 unconjugated
anti-Muscarinic Acetylcholine Receptor M1 (CHRM1) (AA 443-458), (Intracellular) antibodyCHRM1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Anagnostaras, S. G., Murphy, G. G., Hamilton, S. E., Mitchell, S. L., Rahnama, N. P., Nathanson, N. M., Silva, A. J. Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice. Nature Neurosci. 6: 51-58, 2003. 2. Bonner, T. I., Buckley, N. J., Young, A. C., Brann, M. R. Identification of a family of muscarinic acetylcholine receptor genes. Science 237: 527-532, 1987. Note: Erratum: Science 237: 1556 only, 1987. 3. Bonner, T. I., Modi, W. S., Seuanez, H. N., O'Brien, S. J. Chromosomal mapping of five human genes encoding muscarinic acetylcholine receptors. (Abstract) Cytogenet. Cell Genet. 58: 1850-1851, 1991. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
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别名
- CHRM1
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背景
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Synonyms: Muscarinic acetylcholine receptor M1, CHRM1
Tissue Specificity: Sperm. Mainly localized in the tail and in the postacrosomal region but is also found in the midpiece and basal region in a small percentage of sperm cells. Reduced levels found in the sperms of asthenozoospermia and leukocytospermia patients (at protein level). Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.
Background: The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by the CHRM1 gene. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
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分子量
- 55 kDa
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基因ID
- 1128
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UniProt
- P11229
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途径
- Synaptic Membrane
抗原
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