SETDB2 抗体 (C-Term)
Quick Overview for SETDB2 抗体 (C-Term) (ABIN7602746)
抗原
See all SETDB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-CLLD8/SETDB2 Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CLLD8/SETDB2 Picoband® Antibody (ABIN7602746). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CLLD8/SETDB2, which shares 96.6% and 93.1% amino acid (aa) sequence identity with mouse and rat CLLD8/SETDB2, respectively.
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亚型
- IgG
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anti-SET Domain, Bifurcated 2 (SETDB2) (N-Term) antibody
Verified SETDB2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-SET Domain, Bifurcated 2 (SETDB2) (AA 451-550) antibodySETDB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-SET Domain, Bifurcated 2 (SETDB2) (AA 620-719) antibodySETDB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-SET Domain, Bifurcated 2 (SETDB2) (N-Term) antibodySETDB2 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain, Bifurcated 2 (SETDB2) (AA 451-550) antibodySETDB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-SET Domain, Bifurcated 2 (SETDB2) (AA 71-120) antibodySETDB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SET Domain, Bifurcated 2 (SETDB2) (AA 1-280) antibodySETDB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Mabuchi, H., Fujii, H., Calin, G., Alder, H., Negrini, M., Rassenti, L., Kipps, T. J., Bullrich, F., Croce, C. M. Cloning and characterization of CLLD6, CLLD7, CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia. Cancer Res. 61: 2870-2877, 2001. 2. Zhang, Y., Leaves, N. I., Anderson, G. G., Ponting, C. P., Broxholme, J., Holt, R., Edser, P., Bhattacharyya, S., Dunham, A., Adcock, I. M., Pulleyn, L., Barnes, P. J., and 11 others. Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. Nature Genet. 34: 181-186, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
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别名
- SETDB2
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背景
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Synonyms: Histone-lysine N-methyltransferase SETDB2, Chronic lymphocytic leukemia deletion region gene 8 protein, Lysine N-methyltransferase 1F, SET domain bifurcated 2, SETDB2, C13orf4, CLLD8, KMT1F
Tissue Specificity: Highly expressed in reproductive organs, such as testis, ovary and prostate.
Background: SET domain bifurcated histone lysine methyltransferase 2 is a protein in humans encoded by the SETDB2 gene. It is mapped to 13q14.2. This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.
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分子量
- 82 kDa
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基因ID
- 83852
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UniProt
- Q96T68
抗原
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